F Fakhouri, J Zuber, V Frémeaux-Bacchi, C Loirat - The Lancet, 2017 - thelancet.com
Haemolytic uraemic syndrome is a form of thrombotic microangiopathy affecting predominantly the kidney and characterised by a triad of thrombocytopenia, mechanical …
L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA) Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
A Padmanabhan, L Connelly‐Smith… - Journal of clinical …, 2019 - Wiley Online Library
ABSTRACT The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA) Special Issue Writing Committee is charged with reviewing, updating and categorizing …
THJ Goodship, HT Cook, F Fakhouri, FC Fervenza… - Kidney international, 2017 - Elsevier
In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement plays a primary role in disease pathogenesis. Herein we report the outcome of …
NS Merle, R Noe, L Halbwachs-Mecarelli… - Frontiers in …, 2015 - frontiersin.org
The complement system has been considered for a long time as a simple lytic cascade, aimed to kill bacteria infecting the host organism. Nowadays, this vision has changed and it …
As a preformed defense system, complement faces a delicate challenge in providing an immediate, forceful response to pathogens even at first encounter, while sparing host cells in …
F Fakhouri, M Fila, A Hummel, D Ribes… - Blood, The Journal …, 2021 - ashpublications.org
The optimal duration of eculizumab treatment in patients with atypical hemolytic uremic syndrome (aHUS) remains poorly defined. We conducted a prospective national multicenter …
V Brocklebank, KM Wood… - Clinical Journal of the …, 2018 - journals.lww.com
Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury …
JN George, CM Nester - New England Journal of Medicine, 2014 - Mass Medical Soc
Syndromes of Thrombotic Microangiopathy | New England Journal of Medicine Skip to main content The New England Journal of Medicine homepage Advanced Search SEARCH …