This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …

Multipotent retinal progenitors undergo a varied number of divisions to produce clones of
heterogeneous sizes and cell types. We describe the transition from a proliferating …

Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment
melanopsin and regulate a wide array of light-dependent physiological processes …

Approximately 10% of humans with anophthalmia (absent eye) or severe microphthalmia
(small eye) show haploid insufficiency due to mutations in SOX2, a SOXB1-HMG box …

Vascularization is essential for tissue development and in restoration of tissue integrity after
an ischemic injury. In studies of vascularization, the focus has largely been placed on …

In the developing mouse retina, multipotent retinal progenitor cells (RPCs) give rise to
specific retinal cell types at different times, but the molecular mechanisms regulating how …

Our understanding of the development of the retina and visual pathways has seen
enormous advances during the past 25years. New imaging technologies, coupled with …

The timing of cell cycle exit and temporal changes in the developmental competence of
precursor cells are key components for the establishment of the normal complement of cell …

LIM-homeodomain (HD) and POU-HD transcription factors play crucial roles in
neurogenesis. However, it remains largely unknown how they cooperate in this process and …

Previously, we have shown that Onecut1 (Oc1) and Onecut2 (Oc2) are expressed in retinal
progenitor cells, developing retinal ganglion cells (RGCs), and horizontal cells (HCs) …