Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Magnetic nanoparticles in nanomedicine: a review of recent advances

K Wu, D Su, J Liu, R Saha, JP Wang - Nanotechnology, 2019 - iopscience.iop.org
Nanomaterials, in addition to their small size, possess unique physicochemical properties
that differ from bulk materials, making them ideal for a host of novel applications. Magnetic …

The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles

A Abdal Dayem, MK Hossain, SB Lee, K Kim… - International journal of …, 2017 - mdpi.com
Nanoparticles (NPs) possess unique physical and chemical properties that make them
appropriate for various applications. The structural alteration of metallic NPs leads to …

Inflammatory processes in cardiovascular disease: a route to targeted therapies

N Ruparelia, JT Chai, EA Fisher… - Nature reviews …, 2017 - nature.com
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents

J Estelrich, MJ Sánchez-Martín… - International journal of …, 2015 - Taylor & Francis
Magnetic resonance imaging (MRI) has become one of the most widely used and powerful
tools for noninvasive clinical diagnosis owing to its high degree of soft tissue contrast, spatial …

Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy

D Zhi, T Yang, J Yang, S Fu, S Zhang - Acta biomaterialia, 2020 - Elsevier
Among various nanoparticles, superparamagnetic iron oxide nanoparticles (SPIONs) have
been increasingly studied for their excellent superparamagnetism, magnetic heating …

Tissue-penetrating delivery of compounds and nanoparticles into tumors

KN Sugahara, T Teesalu, PP Karmali, VR Kotamraju… - Cancer cell, 2009 - cell.com
Poor penetration of drugs into tumors is a major obstacle in tumor treatment. We describe a
strategy for peptide-mediated delivery of compounds deep into the tumor parenchyma that …

Intraparticle Energy Level Alignment of Semiconducting Polymer Nanoparticles to Amplify Chemiluminescence for Ultrasensitive In Vivo Imaging of Reactive Oxygen …

X Zhen, C Zhang, C Xie, Q Miao, KL Lim, K Pu - ACS nano, 2016 - ACS Publications
Detection of reactive oxygen species (ROS), a hallmark of many pathological processes, is
imperative to understanding, detection and treatment of many life-threatening diseases …

Neuroinflammation after intracerebral hemorrhage

E Mracsko, R Veltkamp - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …

Multifunctional nanoparticles–properties and prospects for their use in human medicine

N Sanvicens, MP Marco - Trends in biotechnology, 2008 - cell.com
A major aim of medicine has long been the early and accurate diagnosis of clinical
conditions, providing an efficient treatment without secondary effects. With the emergence of …