Synthesis of tetrahydropyrans and related heterocycles via prins cyclization; extension to aza-prins cyclization

C Olier, M Kaafarani, S Gastaldi, MP Bertrand - Tetrahedron, 2010 - Elsevier
The Prins reaction 1 is often related to the Kriewitz reaction. 2 The latter leads to unsaturated
alcohol 1 from a-pinene and formaldehyde through a thermal 'ene-rearrangement'(Eq. 1) …

Applications of Wittig reaction in the total synthesis of natural macrolides

MM Heravi, V Zadsirjan, M Daraie… - …, 2020 - Wiley Online Library
The Wittig reaction involves the synthesis of an alkene via the conversion of an aldehyde or
ketone with the already generated ylide from a phosphonium salt. Significantly, when this …

An environmentally benign synthesis of octahydro-2H-chromen-4-ols via modified montmorillonite K10 catalyzed Prins cyclization reaction

G Baishya, B Sarmah, N Hazarika - Synlett, 2013 - thieme-connect.com
(–)-Isopulegol undergoes Prins cyclization reaction in the presence of 20 wt% of acid-treated
montmorillonite K10 to produce octahydro-2H-chromen-4-ols in good yields and with high …

A concise stereoselective formal total synthesis of the cytotoxic macrolide (+)-Neopeltolide via Prins cyclization

JS Yadav, GG Krishana, SN Kumar - Tetrahedron, 2010 - Elsevier
A concise stereoselective formal total synthesis of the cytotoxic macrolide (+)-Neopeltolide via
Prins cyclization - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

Laboratory scale-up synthesis of chiral carbinols using Rhizopus arrhizus

NA Salvi, S Chattopadhyay - Tetrahedron: Asymmetry, 2016 - Elsevier
Rhizopus arrhizus mediated bioreduction was optimized using acetophenone as a model
substrate. Various parameters such as bio-processing conditions, reaction time, substrate …

Total synthesis of (+/−)-diospongin A via Prins reaction

MA Hiebel, B Pelotier, O Piva - Tetrahedron, 2007 - Elsevier
Total synthesis of (+/−)-diospongin A via Prins reaction - ScienceDirect Skip to main contentSkip
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Bioinspired iterative synthesis of polyketides

K Zheng, C Xie, R Hong - Frontiers in Chemistry, 2015 - frontiersin.org
Diverse array of biopolymers and second metabolites (particularly polyketide natural
products) has been manufactured in nature through an enzymatic iterative assembly of …

Synthetic applications of Prins cyclization in natural product syntheses

K Tadiparthi, A Roy, R Sakirolla… - The Chemical …, 2022 - Wiley Online Library
The natural products having tetrahydropyran unit with multiple chiral centers serve as
magnificent building blocks for various active pharmaceutical ingredients (APIs).'Prins …

De novo synthesis of natural products via the asymmetric hydration of polyenes

Y Wang, Y Xing, Q Zhang, GA O'Doherty - Chemical Communications, 2011 - pubs.rsc.org
For the last ten years our group has been working toward the development of an asymmetric
hydration approach to polyketide natural products based on the regioselective hydration of …

Stereoselective total synthesis of decarestrictine-J via Ring Closing Metathesis (RCM)

JS Yadav, KA Lakshmi, NM Reddy, AR Prasad… - Tetrahedron, 2010 - Elsevier
Stereoselective total synthesis of decarestrictine-J via Ring Closing Metathesis (RCM) -
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