Acinetobacter baumannii: human infections, factors contributing to pathogenesis and animal models

MJ McConnell, L Actis, J Pachón - FEMS microbiology reviews, 2013 - academic.oup.com
Acinetobacter baumannii has emerged as a medically important pathogen because of the
increasing number of infections produced by this organism over the preceding three …

Treatment of Acinetobacter Infections

J Fishbain, AY Peleg - Clinical infectious diseases, 2010 - academic.oup.com
Acinetobacter baumannii remains an important and difficult-to-treat pathogen whose
resistance patterns result in significant challenges for the clinician. Despite the prevalence …

Multidrug-resistant Gram-negative bacteria: how to treat and for how long

H Giamarellou - International journal of antimicrobial agents, 2010 - Elsevier
The emergence of multidrug-resistant (MDR) Gram-negative bacilli creates a big problem for
the treatment of nosocomial infections. As the pharmaceutical pipeline wanes, the only …

Intraventricular and intrathecal colistin as the last therapeutic resort for the treatment of multidrug-resistant and extensively drug-resistant Acinetobacter baumannii …

I Karaiskos, L Galani, F Baziaka… - International journal of …, 2013 - Elsevier
Acinetobacter baumannii ventriculitis/meningitis due to the emergence of multidrug-resistant
(MDR) and extensively drug-resistant (XDR) strains has become a clinical entity of …

Recent Advances in the Pursuit of an Effective Acinetobacter baumannii Vaccine

PS Gellings, AA Wilkins, LA Morici - Pathogens, 2020 - mdpi.com
Acinetobacter baumannii has been a major cause of nosocomial infections for decades. The
absence of an available vaccine coupled with emerging multidrug resistance has prevented …

Therapeutic options for Acinetobacter baumannii infections: an update

J Vila, J Pachon - Expert opinion on pharmacotherapy, 2012 - Taylor & Francis
Introduction: Although the clinical importance of Acinetobacter pittii and Acinetobacter
nosocomialis has increased in the nosocomial setting in the last decade, infections caused …

Membrane vesicles derived from gut microbiota and probiotics: Cutting-edge therapeutic approaches for multidrug-resistant superbugs linked to neurological …

P Srivastava, K Kim - Pharmaceutics, 2022 - mdpi.com
Multidrug-resistant (MDR) superbugs can breach the blood–brain barrier (BBB), leading to a
continuous barrage of pro-inflammatory modulators and induction of severe infection-related …

Intraventricular versus intravenous colistin for the treatment of extensively drug resistant Acinetobacter baumannii meningitis

P De Bonis, G Lofrese, G Scoppettuolo… - European journal of …, 2016 - Wiley Online Library
Background and purpose Reports on the safety and efficacy of intraventricularly
administered (IVT) colistin for the treatment of Acinetobacter baumannii ventriculomeningitis …

Bundle of measures for external cerebral ventricular drainage-associated ventriculitis

M Chatzi, M Karvouniaris, D Makris… - Critical care …, 2014 - journals.lww.com
Objective: To assess the prevalence and outcome of external cerebral ventricular drainage-
associated ventriculitis in neurocritical patients before and after the implementation of a …

Surveillance and management of multidrug-resistant microorganisms

GB Orsi, M Falcone, M Venditti - Expert Review of Anti-Infective …, 2011 - Taylor & Francis
Multidrug-resistant organisms are an established and growing worldwide public health
problem and few therapeutic options remain available. The traditional antimicrobials …