Molecular characterization of Ebola virus, immune response, and therapeutic challenges: a narrative review
The Ebola virus (EBOV) remains a major public health challenge due to its complex
structure and the lack of appropriate and effective vaccines and therapies. This review …
structure and the lack of appropriate and effective vaccines and therapies. This review …
Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeutics
HN Lee, B Xu, AP Lewkowicz, K Engel… - …, 2024 - thelancet.com
Background Ebola virus disease (EVD) survivors experience ocular sequelae including
retinal lesions, cataracts, and vision loss. While monoclonal antibodies targeting the Ebola …
retinal lesions, cataracts, and vision loss. While monoclonal antibodies targeting the Ebola …
Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease
TG Wanninger, OA Saldarriaga, E Arroyave… - Frontiers in …, 2024 - frontiersin.org
Background The inflammatory macrophage response contributes to severe Ebola virus
disease, with liver and lung injury in humans. Objective We sought to further define the …
disease, with liver and lung injury in humans. Objective We sought to further define the …
[HTML][HTML] Human macrophages infected with Egyptian Rousette bat-isolated Marburg virus display inter-individual susceptibility and antiviral responsiveness
IA Yordanova, A Lander, A Wahlbrink, JS Towner… - npj Viruses, 2024 - nature.com
Marburg virus (MARV) is a highly pathogenic filovirus and a causative agent of sporadic
zoonotic viral hemorrhagic fever outbreaks with high case fatality rates. In humans …
zoonotic viral hemorrhagic fever outbreaks with high case fatality rates. In humans …