Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Spinal cord injury (SCI), a serious public health issue, most likely occurs in previously
healthy young adults. Current therapeutic strategies for SCI includes surgical …

Objective Neuronal channelopathies cause brain disorders, including epilepsy, migraine,
and ataxia. Despite the development of mouse models, pathophysiological mechanisms for …

The greatest therapeutic promise of human embryonic stem cells (hESC) is to generate
specialized cells to replace damaged tissue in patients suffering from various degenerative …

Spinal cord injury (SCI) causes myelopathy, damage to white matter, and myelinated fiber
tracts that carry sensation and motor signals to and from the brain. The gray matter damage …

Neural progenitor cells have been proposed as a therapy for central nervous system
disorders, including neurodegenerative diseases and trauma injuries, however their …

In extensive bone defects, tissue damage and hypoxia lead to cell death, resulting in slow
and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized …

Human embryonic stem cells (hESC) hold great promise for the treatment of patients with
many neurodegenerative diseases particularly those arising from cell loss or neural …

Efficient derivation of large-scale motor neurons (MNs) from human pluripotent stem cells is
central to the understanding of MN development, modelling of MN disorders in vitro and …

Availability of human embryonic stem cells (hESC) has enhanced human neural
differentiation research. The derivation of neural progenitor (NP) cells from hESC facilitates …