Control of key metabolic intersections in Bacillus subtilis
AL Sonenshein - Nature Reviews Microbiology, 2007 - nature.com
The remarkable ability of bacteria to adapt efficiently to a wide range of nutritional
environments reflects their use of overlapping regulatory systems that link gene expression …
environments reflects their use of overlapping regulatory systems that link gene expression …
Control of glutamate homeostasis in Bacillus subtilis: a complex interplay between ammonium assimilation, glutamate biosynthesis and degradation
K Gunka, FM Commichau - Molecular microbiology, 2012 - Wiley Online Library
Glutamate, the major amino group donor in anabolism, is synthesized by the combined
action of the glutamine synthetase (GS) and the glutamate synthase (GOGAT) in Bacillus …
action of the glutamine synthetase (GS) and the glutamate synthase (GOGAT) in Bacillus …
Differential Effects of Epinephrine, Norepinephrine, and Indole on Escherichia coli O157:H7 Chemotaxis, Colonization, and Gene Expression
During infection in the gastrointestinal tract, enterohemorrhagic Escherichia coli (EHEC)
O157: H7 is exposed to a wide range of signaling molecules, including the eukaryotic …
O157: H7 is exposed to a wide range of signaling molecules, including the eukaryotic …
Iron deficiency accelerates Helicobacter pylori–induced carcinogenesis in rodents and humans
Gastric adenocarcinoma is strongly associated with Helicobacter pylori infection; however,
most infected persons never develop this malignancy. H. pylori strains harboring the cag …
most infected persons never develop this malignancy. H. pylori strains harboring the cag …
Repression of Clostridium difficile toxin gene expression by CodY
SS Dineen, AC Villapakkam, JT Nordman… - Molecular …, 2007 - Wiley Online Library
CodY, a global regulator of gene expression in low G+ C Gram‐positive bacteria, was found
to repress toxin gene expression in Clostridium difficile. Inactivation of the codY gene …
to repress toxin gene expression in Clostridium difficile. Inactivation of the codY gene …
Airway metabolic profiling during Streptococcus pneumoniae infection identifies branched chain amino acids as signatures of upper airway colonisation
Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and
bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to …
bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to …
The cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae
High levels of copper are toxic and therefore bacteria must limit free intracellular levels to
prevent cellular damage. In this study, we show that a number of pneumococcal genes are …
prevent cellular damage. In this study, we show that a number of pneumococcal genes are …
CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae
In Gram-positive bacteria, the transcriptional regulator CcpA is at the core of catabolite
control mechanisms. In the human pathogen Streptococcus pneumoniae, links between …
control mechanisms. In the human pathogen Streptococcus pneumoniae, links between …
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae
A Minnen, L Attaiech, M Thon, S Gruber… - Molecular …, 2011 - Wiley Online Library
Segregation of replicated chromosomes is an essential process in all organisms. How
bacteria, such as the oval‐shaped human pathogen Streptococcus pneumoniae, efficiently …
bacteria, such as the oval‐shaped human pathogen Streptococcus pneumoniae, efficiently …
Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria
BA Travis, JV Peck, R Salinas, B Dopkins… - Nature …, 2022 - nature.com
How bacteria sense and respond to nitrogen levels are central questions in microbial
physiology. In Gram-positive bacteria, nitrogen homeostasis is controlled by an operon …
physiology. In Gram-positive bacteria, nitrogen homeostasis is controlled by an operon …