[HTML][HTML] Molecular targeted therapy of cancer: The progress and future prospect

X Ke, L Shen - Frontiers in Laboratory Medicine, 2017 - Elsevier
Cancer has become a major public health problem worldwide. Researches focus on the
new approaches for cancer treatments that involve the specific targets of the cancer disease …

[HTML][HTML] Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells

Y Zhao, H Tang, X Zeng, D Ye, J Liu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Recent studies have shown that resveratrol (RES) inhibits cancer cell growth, migration and
invasion. Here, we evaluated RES in two human renal cell carcinoma (RCC) cell lines …

[HTML][HTML] Novel systemic therapy against malignant pleural mesothelioma

MR Mancuso, JW Neal - Translational Lung Cancer Research, 2017 - ncbi.nlm.nih.gov
Malignant pleural mesothelioma is an aggressive tumor of the pleura with an overall poor
prognosis. Even with surgical resection, for which only a subset of patients are eligible, long …

Role of miR‐486‐5p in regulating renal cell carcinoma cell proliferation and apoptosis via TGF‐β–activated kinase 1

Y He, J Liu, Y Wang, X Zhu, Z Fan, C Li… - Journal of Cellular …, 2019 - Wiley Online Library
Renal cell carcinoma (RCC) is a common kidney tumor in adults. The role of miR‐486‐5p in
RCC is unknown. The aim of our study was to identify new targets regulated by miR‐486‐5p …

Tumor suppressor miR-211-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma

J Quan, X Pan, T He, C Lin, Y Lai… - Experimental and …, 2018 - spandidos-publications.com
Increasing evidence has demonstrated that microRNA (miRNA) serve an important role in
the tumorigenesis of various types of cancer, such as renal cell carcinoma (RCC). The …

Upregulation of long noncoding RNA PVT1 predicts unfavorable prognosis in patients with clear cell renal cell carcinoma

X Bao, J Duan, Y Yan, X Ma, Y Zhang… - Cancer …, 2018 - content.iospress.com
BACKGROUND: Renal cell carcinoma (RCC) is one of the most malignant genitourinary
diseases worldwide. Long noncoding RNAs (lncRNAs) are a class of noncoding RNAs in …

The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma

H Polena, J Creuzet, M Dufies, A Sidibé… - British Journal of …, 2018 - nature.com
Background Vascular endothelial (VE)-cadherin is an endothelial cell-specific protein
responsible for endothelium integrity. Its adhesive properties are regulated by post …

Ubiquitin specific peptidase 19 is a prognostic biomarker and affect the proliferation and migration of clear cell renal cell carcinoma

W Hu, Y Su, X Fei, X Wang, G Zhang… - Oncology …, 2020 - spandidos-publications.com
Abstract Ubiquitin specific peptidase 19 (USP19) is a member of the USP family and exhibits
diverse roles in various biological processes, such as cell differentiation, cell cycle …

Downregulation of microRNA-15a suppresses the proliferation and invasion of renal cell carcinoma via direct targeting of eIF4E

G Li, T Chong, X Xiang, J Yang… - Oncology reports, 2017 - spandidos-publications.com
The downregulation of microRNA-15a has been reported in several human tumors.
However, its expression and functional importance in renal cell carcinoma (RCC) remain …

[HTML][HTML] HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1α and HIF-2α balance in renal cell carcinoma

XM Lai, SY Liu, YT Tsai, GH Sun, SY Chang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Anti-angiogenesis has emerged as a standard of care for metastatic renal cell carcinoma.
However, long-lasting efficacy is seldom reached, and evasive resistance eventually occurs …