Mechanisms of endothelial flow sensing
C Aitken, V Mehta, MA Schwartz, E Tzima - Nature Cardiovascular …, 2023 - nature.com
Fluid shear stress plays a key role in sculpting blood vessels during development, in adult
vascular homeostasis and in vascular pathologies. During evolution, endothelial cells …
vascular homeostasis and in vascular pathologies. During evolution, endothelial cells …
[HTML][HTML] Angiotensin II Exposure In Vitro Reduces High Salt-Induced Reactive Oxygen Species Production and Modulates Cell Adhesion Molecules' Expression in …
N Kolobarić, N Kozina, Z Mihaljević… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Objectives: Increased sodium chloride (NaCl) intake led to leukocyte activation
and impaired vasodilatation via increased oxidative stress in human/animal models …
and impaired vasodilatation via increased oxidative stress in human/animal models …
Is there association between altered adrenergic system activity and microvascular endothelial dysfunction induced by a 7-day high salt intake in young healthy …
This study aimed to test the effect of a 7-day high-salt (HS) diet on autonomic nervous
system (ANS) activity in young healthy individuals and modulation of ANS on microvascular …
system (ANS) activity in young healthy individuals and modulation of ANS on microvascular …
The role of angiotensin II type 1 receptor pathway in cerebral ischemia‒reperfusion injury: Implications for the neuroprotective effect of ARBs
S Huang, M Zhang - Neuroprotection, 2024 - Wiley Online Library
Cerebral ischemia–reperfusion (I/R) injury is a crucial factor that impacts the prognosis of
recanalization therapy for acute ischemic stroke (AIS). It has been found that the brain renin …
recanalization therapy for acute ischemic stroke (AIS). It has been found that the brain renin …
[HTML][HTML] Oral Carnosine Supplementation Preserves Vascular Function of Sprague Dawley Rats on a High-Salt Diet via Restored Antioxidative Defence
Backgrounds/Objectives: Following previous findings on high-salt (HS)-intake-related
increase of oxidative stress, this study explored whether carnosine (CAR; β-alanyl-L …
increase of oxidative stress, this study explored whether carnosine (CAR; β-alanyl-L …
Piper sarmentosum Roxb. Inhibits Angiotensin-Converting Enzyme Activity in Phorbol 12-Myristate-13-Acetate-Induced Endothelial Cells
Angiotensin-converting enzyme (ACE) plays a crucial role in the pathogenesis of
hypertension. Piper sarmentosum Roxb., an herb known for its antihypertensive effect, lacks …
hypertension. Piper sarmentosum Roxb., an herb known for its antihypertensive effect, lacks …
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2
Y He, H Su, N Li, Y Zhang, P Zhang, Y Zhang… - Hypertension …, 2022 - nature.com
Hypoxia can lead to adult middle cerebral artery (MCA) dysfunction and increase the risk of
cerebrovascular diseases. It is largely unknown whether intrauterine hypoxia affects fetal …
cerebrovascular diseases. It is largely unknown whether intrauterine hypoxia affects fetal …
Molecular pathomechanisms of impaired flow-induced constriction of cerebral arteries following traumatic brain injury: a potential impact on cerebral autoregulation
(1) Background: Traumatic brain injury (TBI) frequently occurs worldwide, resulting in high
morbidity and mortality. Here, we hypothesized that TBI impairs an autoregulatory …
morbidity and mortality. Here, we hypothesized that TBI impairs an autoregulatory …
The Effect of High-Salt Diet on Oxidative Stress Production and Vascular Function in Tff3−/−/C57BL/6N Knockout and Wild Type (C57BL/6N) Mice
N Kozina, I Jukić, Z Mihaljević, A Matić… - Journal of Vascular …, 2024 - karger.com
Introduction: It is well documented that high-salt (HS) diet increases systemic and vascular
oxidative stress in various animal models and in humans, leading to impairment of vascular …
oxidative stress in various animal models and in humans, leading to impairment of vascular …
Low-dose angiotensin II supplementation restores flow-induced dilation mechanisms in cerebral arteries of Sprague-Dawley rats on a high salt diet
Objective: Salt-induced suppression of angiotensin II contributes to impaired endothelium-
dependent vascular reactivity. The present study investigated the effect of chronic low-dose …
dependent vascular reactivity. The present study investigated the effect of chronic low-dose …