Prebiotics, probiotics, synbiotics, paraprobiotics and postbiotic compounds in IBD

A Martyniak, A Medyńska-Przęczek, A Wędrychowicz… - Biomolecules, 2021 - mdpi.com
The increasing incidence of inflammatory bowel diseases (IBD) and the increasing severity
of the course of these diseases create the need for developing new methods of therapy. The …

Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism

J Gao, K Xu, H Liu, G Liu, M Bai, C Peng… - Frontiers in cellular and …, 2018 - frontiersin.org
The gut microbiota influences the health of the host, especially with regard to gut immune
homeostasis and the intestinal immune response. In addition to serving as a nutrient …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

GZ Wei, KA Martin, PY Xing… - Proceedings of the …, 2021 - National Acad Sciences
While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …

Shaping the gut microbiota by breastfeeding: the gateway to allergy prevention?

LWJ Van den Elsen, J Garssen, R Burcelin… - Frontiers in …, 2019 - frontiersin.org
Evidence is accumulating that demonstrates the importance of the gut microbiota in health
and diseases such as allergy. Recent studies emphasize the importance of the “window of …

Incomplete systemic recovery and metabolic phenoreversion in post-acute-phase nonhospitalized COVID-19 patients: implications for assessment of post-acute …

E Holmes, J Wist, R Masuda, S Lodge… - Journal of proteome …, 2021 - ACS Publications
We present a multivariate metabotyping approach to assess the functional recovery of
nonhospitalized COVID-19 patients and the possible biochemical sequelae of “Post-Acute …

Lactobacillus lactis and Pediococcus pentosaceus‐driven reprogramming of gut microbiome and metabolome ameliorates the progression of non‐alcoholic fatty …

JS Yu, GS Youn, J Choi, CH Kim… - Clinical and …, 2021 - Wiley Online Library
Background Although microbioa‐based therapies have shown putative effects on the
treatment of non‐alcoholic fatty liver disease (NAFLD), it is not clear how microbiota‐derived …

The role of the aryl hydrocarbon receptor (AHR) in immune and inflammatory diseases

DR Neavin, D Liu, B Ray… - International journal of …, 2018 - mdpi.com
The aryl hydrocarbon receptor (AHR) is a nuclear receptor that modulates the response to
environmental stimuli. It was recognized historically for its role in toxicology but, in recent …

Butyrate acts through HDAC inhibition to enhance aryl hydrocarbon receptor activation by gut microbiota-derived ligands

M Modoux, N Rolhion, JH Lefevre, C Oeuvray… - Gut …, 2022 - Taylor & Francis
Aryl hydrocarbon receptor (AhR) is a critical player in the crosstalk between the gut
microbiota and its host. However, factors regulating AhR within the gut, which is a complex …

Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome

JM Natividad, A Agus, J Planchais, B Lamas, AC Jarry… - Cell metabolism, 2018 - cell.com
The extent to which microbiota alterations define or influence the outcome of metabolic
diseases is still unclear, but the byproducts of microbiota metabolism are known to have an …