Persistent infection with human papillomavirus (HPV) initiates~ 5% of all human cancers,
and particularly cervical and oropharyngeal cancers. HPV vaccines prevent HPV infection …

Nucleic acid sensors, primarily TLR and RLR family members, as well as cGAS–STING
signalling, play a critical role in the preservation of cellular and organismal homeostasis …

The effective treatment of advanced cervical cancer remains challenging. Herein, single‐
nucleus RNA sequencing (snRNA‐seq) and SpaTial enhanced resolution omics …

Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a bridging
role in innate immunity and adaptive immunity. The activated TLRs not only induce …

During the early stages of human papillomavirus (HPV) infections, the innate immune
system creates a pro-inflammatory microenvironment by recruiting innate immune cells to …

Background: Vulval intraepithelial neoplasia (VIN) is a premalignant condition, which is
frequently associated with type HPV16 infection, and multifocal disease has high rates of …

Objectives: To review evidence for the role of human papillomavirus (HPV) in the etiology of
oropharyngeal cancers, methods of viral detection, and the resulting clinical implications …

Carcinomas of the anogenital tract, in particular cervical cancer, remains one of the most
common cancers in women, and represent the most frequent gynecological malignancies …

Recent findings show that Toll-like receptors (TLRs) expressed in immune cells play a
crucial role in the innate immune response and the subsequent induction of adaptive …

The recent development of vaccines prophylactic against human papillomavirus (HPV)
infection has the potential to reduce the incidence of cervical cancer globally by up to 70 …