Genetic factors in mammalian prion diseases
S Mead, S Lloyd, J Collinge - Annual review of genetics, 2019 - annualreviews.org
Mammalian prion diseases are a group of neurodegenerative conditions caused by infection
of the central nervous system with proteinaceous agents called prions, including sporadic …
of the central nervous system with proteinaceous agents called prions, including sporadic …
A 14-bp functional deletion within the CMTM2 gene is significantly associated with litter size in goat
Z Kang, S Zhang, L He, H Zhu, Z Wang, H Yan… - Theriogenology, 2019 - Elsevier
CKLF-like MARVEL transmembrane domain-containing 2 (CMTM2) plays an important role
in animal reproduction, and abnormal CMTM2 expression leads to spermatogenesis …
in animal reproduction, and abnormal CMTM2 expression leads to spermatogenesis …
Application of mathematical expectation (ME) strategy for detecting low frequency mutations: An example for evaluating 14-bp insertion/deletion (indel) within the …
Q Yang, S Zhang, L Liu, X Cao, C Lei, X Qi, F Lin, W Qu… - Prion, 2016 - Taylor & Francis
The detection method based on the mathematical expectation (ME) strategy is fast and
accuracy for low frequency mutation screening in large samples. Previous studies have …
accuracy for low frequency mutation screening in large samples. Previous studies have …
Structure of the prion protein and its gene: an analysis using bioinformatics and computer simulation
Prion protein (PrP) gene encodes cellular PrP (PrPC), a glycosylphosphatidylinositol (GPI)-
anchored cell membrane protein indispensable for infections of prion, which causes …
anchored cell membrane protein indispensable for infections of prion, which causes …
PRNP gene variation in Pakistani cattle and buffaloes
Bovine spongiform encephalopathy (BSE) is a neurodegenerative prion protein misfolding
disorder of cattle. BSE is of two types, classical BSE and atypical BSE which in turn is of two …
disorder of cattle. BSE is of two types, classical BSE and atypical BSE which in turn is of two …
PRNP haplotype associated with classical BSE incidence in European Holstein cattle
Background Classical bovine spongiform encephalopathy (BSE) is an acquired prion
disease of cattle. The bovine prion gene (PRNP) contains regions of both high and low …
disease of cattle. The bovine prion gene (PRNP) contains regions of both high and low …
Indels within promoter and intron 1 of bovine prion protein gene modulate the gene expression levels in the medulla oblongata of two Japanese cattle breeds
Genetic differences which exist in the prion protein gene (PRNP) have been reported to
influence susceptibility of humans, sheep and goats to prion diseases. In cattle, however …
influence susceptibility of humans, sheep and goats to prion diseases. In cattle, however …
Comparative Analysis of PRNP Gene Indel Polymorphism and Expression among Zhongdian Yellow Cattle, Zhongdian Yak, and Their Hybrids
X He, S Memon, D Yue, J Zhu, Y Lu, X Liu, H Xiong… - Animals, 2023 - mdpi.com
Simple Summary Bovine spongiform encephalopathy (BSE), a neurological disorder with a
significant effect on cattle health, has been recognized pathologically and medically. It is …
significant effect on cattle health, has been recognized pathologically and medically. It is …
Bovine spongiform encephalopathy associated insertion/deletion polymorphisms of the prion protein gene in the four beef cattle breeds from North China
XY Zhu, FY Feng, SY Xue, T Hou, HR Liu - Genome, 2011 - cdnsciencepub.com
Two insertion/deletion (indel) polymorphisms of the prion protein gene (PRNP), a 23-bp
indel in the putative promoter region and a 12-bp indel within intron I, are associated with …
indel in the putative promoter region and a 12-bp indel within intron I, are associated with …
Polymorphism of the prion protein gene (PRNP) in Polish cattle affected by classical bovine spongiform encephalopathy
Recent attempts to discover genetic factors affecting cattle resistance/susceptibility to bovine
spongiform encephalopathy (BSE) have led to the identification of two insertion/deletion …
spongiform encephalopathy (BSE) have led to the identification of two insertion/deletion …