Populations with common physical diseases–such as cardiovascular diseases, cancer and
neurodegenerative disorders–experience substantially higher rates of major depressive …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …

Background Information on the frequency and timing of mental disorder onsets across the
lifespan is of fundamental importance for public health planning. Broad, cross-national …

Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …

Mental disorders account for a large and increasing health burden worldwide, as shown in
the Global Burden of Diseases (GBD) Study 2010. Unpacking how this burden in children …

Abstract Knowledge on psychiatric comorbidity in adult ADHD is essential for prevention,
detection, and treatment of these conditions. This review (1) focuses on large studies (n> …

An extensive literature regarding gender differences relevant to several aspects of
schizophrenia is nowadays available. It includes some robust findings as well as some …

Background Patients suffering from severe mental disorders, including schizophrenia, major
depression and bipolar disorders, have a reduced life expectancy compared to the general …

Background There is increasing research examining excess mortality in people with bipolar
disorder using life expectancy and related measures, which quantify the disease impact on …

Background Mental disorders are associated with premature mortality. There is increasing
research examining life expectancy and years-of-potential-life-lost (YPLL) to quantify the …