Human microbiota research in Africa: a systematic review reveals gaps and priorities for future research

I Allali, RE Abotsi, LA Tow, L Thabane, HJ Zar… - Microbiome, 2021 - Springer
Background The role of the human microbiome in health and disease is an emerging and
important area of research; however, there is a concern that African populations are under …

Personalizing medicine in Africa: current state, progress and challenges

P Owolabi, Y Adam, E Adebiyi - Frontiers in Genetics, 2023 - frontiersin.org
Personalized medicine has been identified as a powerful tool for addressing the myriad of
health issues facing different health systems globally. Although recent studies have …

Equity in international health research collaborations in Africa: perceptions and expectations of African researchers

NS Munung, BM Mayosi, J de Vries - PloS one, 2017 - journals.plos.org
Introduction and method Africa is currently host to a number of international genomics
research and biobanking consortia, each with a mandate to advance genomics research …

Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions

S Fatumo, D Sathan, C Samtal, I Isewon, T Tamuhla… - Genome Medicine, 2023 - Springer
Early identification of genetic risk factors for complex diseases can enable timely
interventions and prevent serious outcomes, including mortality. While the genetics …

Expanding research capacity in Sub-Saharan Africa through informatics, bioinformatics, and data science training programs in Mali

JG Shaffer, FJ Mather, M Wele, J Li, CO Tangara… - Frontiers in …, 2019 - frontiersin.org
Bioinformatics and data science research have boundless potential across Africa due to its
high levels of genetic diversity and disproportionate burden of infectious diseases, including …

Building local capacity for genomics research in Africa: recommendations from analysis of publications in Sub-Saharan Africa from 2004 to 2013

BO Adedokun, CO Olopade, OI Olopade - Global Health Action, 2016 - Taylor & Francis
Background The poor genomics research capacity of Sub-Saharan Africa (SSA) could
prevent maximal benefits from the applications of genomics in the practice of medicine and …

Alteration of the gut fecal microbiome in children living with HIV on antiretroviral therapy in Yaounde, Cameroon

WB Abange, C Martin, AJ Nanfack, LG Yatchou… - Scientific Reports, 2021 - nature.com
Multiple factors, such as immune disruption, prophylactic co-trimoxazole, and antiretroviral
therapy, may influence the structure and function of the gut microbiome of children infected …

Human OMICs and computational biology research in Africa: current challenges and prospects

Y Hamdi, L Zass, H Othman, F Radouani… - OMICS: A Journal of …, 2021 - liebertpub.com
Following the publication of the first human genome, OMICs research, including genomics,
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …

Genomics in Egypt: current status and future aspects

EA El-Attar, RM Helmy Elkaffas, SA Aglan… - Frontiers in …, 2022 - frontiersin.org
Egypt is the third most densely inhabited African country. Due to the economic burden and
healthcare costs of overpopulation, genomic and genetic testing is a huge challenge …

Bioinformatics mentorship in a resource limited setting

D Jjingo, G Mboowa, I Sserwadda… - Briefings in …, 2022 - academic.oup.com
Background The two recent simultaneous developments of high-throughput sequencing and
increased computational power have brought bioinformatics to the forefront as an important …