Small ubiquitin-like modifiers (SUMOs) are essential for the regulation of several cellular
processes and are potential therapeutic targets owing to their involvement in diseases such …

Post-translational protein modification by small ubiquitin-like modifier (SUMO), termed
sumoylation, is an important mechanism in cellular responses to stress and one that …

Small ubiquitin-like modifiers (SUMOs) are post-translational modifications (PTMs) that
regulate nuclear cellular processes. Here we used an augmented K0–SUMO proteomics …

DNA double-strand breaks (DSBs) are highly cytotoxic DNA lesions. The swift recognition
and faithful repair of such damage is crucial for the maintenance of genomic stability, as well …

Protein conjugation with Small ubiquitin-like modifier (SUMOylation) has critical roles during
cell cycle progression. Many important cell cycle regulators, including many oncogenes and …

Small ubiquitin-like modifiers (SUMOs) are post-translational modifications that play crucial
roles in most cellular processes. While methods exist to study exogenous SUMOylation …

Preserving genome function and stability are paramount for ensuring cellular homeostasis,
an imbalance in which can promote diseases including cancer. In the presence of DNA …

A timely and accurate cellular response to DNA damage requires tight regulation of the
action of DNA damage response (DDR) proteins at lesions. A multitude of posttranslational …

Histone methylation plays fundamental roles in regulating chromatin‐based processes. With
the discovery of histone demethylases over a decade ago, it is now clear that histone …

Transactive response DNA binding protein (TDP-43) is a key player in neurodegenerative
diseases. In this review, we have gathered and presented structural information on the …