Transcription factors (TFs) are essential players in orchestrating the regulatory landscape in
cells. Still, their exact modes of action and dependencies on other regulatory aspects remain …

Antibodies offer a powerful means to interrogate specific proteins in a complex milieu.
However, antibody availability and reliability can be problematic, whereas epitope tagging …

Motivation The activity of a transcription factor (TF) in a sample of cells is the extent to which
it is exerting its regulatory potential. Many methods of inferring TF activity from gene …

The discovery of functional cancer drivers has traditionally focused on mutations within
coding regions of DNA, despite these regions comprising only about 2% of the entire …

Transcription factors (TFs) are a set of proteins that play a key role in the information
processing system that enables a cell to respond to changes in internal and external state …

Antibodies offer a powerful means to interrogate specific proteins in a complex milieu.
However, antibody availability and reliability are problematic and epitope tagging can be …

The discovery of functional cancer drivers has traditionally focused on mutations within
coding regions of DNA, despite these regions comprising only about 2% of the entire …

Gene regulation is one of the most important cellular processes and closely interlinked
pathogenesis. The elucidation of regulatory mechanisms can be approached by many …

Recognizing familiar faces and learning new faces play an important role in social cognition.
However, the underlying neural computational mechanisms remain unclear. Here, we …