Evolutionary and comparative approaches can yield novel insights into human adaptation
and disease. Endometriosis and polycystic ovary syndrome (PCOS) each affect up to 10% of …

Testosterone (T) is the predominant endogenous androgen in the bloodstream. At the
vascular level, T presents genomic and non-genomic effects, and both effects may overlap …

Abstract Background and Aims Availability of age‐and sex‐specific reference values for sex
steroids and sex steroid‐binding globulin (SHBG) levels allows for appropriate interpretation …

Obesity has been linked to an increased risk of and a worse prognosis for several types of
cancer. A number of interrelated mediators contribute to obesity's pro-tumor effects …

In men, 70% of circulating testosterone binds with high affinity to plasma sex hormone
binding globulin (SHBG), which determines its bioavailability in their target cells. In recent …

Background A complex relationship between adipose tissue and malignancy, involving an
inflammatory response, has been reported. The goal of this work was to assess the …

PCOS is one of the most common endocrine disorders and NAFLD is one of its most
dangerous metabolic consequences. The diagnosis of NAFLD is not a practical task and the …

Sedentary lifestyle accelerates biological ageing, is a major risk factor for developing
metabolic syndrome and is associated with cardiovascular disease, diabetes mellitus …

Introduction Environmental pollutants could be implicated in female endocrine setting Q6
beyond traditional factors. Until now, few study has focused on the association of …

Abstract Background & Aims Incidence rates of liver cancer in most populations are two to
three times higher among men than women. The higher rates among men have led to the …