Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

The advent of drug-resistant pathogens results in the occurrence of stubborn bacterial
infections that cannot be treated with traditional antibiotics. Antibacterial immunotherapy by …

Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …

Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

Hospital-acquired infections, also known as nosocomial infections, include bloodstream
infections, surgical site infections, skin and soft tissue infections, respiratory tract infections …

In vitro biofilms are communities of microbes with unique features compared to individual
cells. Biofilms are commonly characterized by physical traits like size, adhesion, and a …

Sepsis is a life-threatening condition characterized by an uncontrolled inflammatory
response to an infectious agent and its antigens. Immune cell activation against the antigens …

Bacterial biofilms can be found in most environments on our planet, and the human body is
no exception. Consisting of microbial cells encased in a matrix of extracellular polymers …

Laboratory models are critical to basic and translational microbiology research. Models
serve multiple purposes, from providing tractable systems to study cell biology to allowing …