Copper-catalyzed cross-coupling reactions which lead to the formation of C–N, C–O, C–S
and C–C bonds have been recognized as one of the most useful strategies in synthetic …

The last century represents an exciting era for the chemical evolution of transition-metal
catalyzed reactions, 1–3 and among these, the chemistry of palladium, 4–6 ruthenium, 7–10 …

A metal-free cross-dehydrogenative coupling between quinoxalinones (sp2 C–H) and
amines (N–H) in the presence of catalytic iodine is reported. The reaction yields 3 …

The bromodomain and extra-terminal domain (BET) family of proteins bind acetylated lysine
residues on histone proteins. The four BET bromodomains—BRD2, BRD3, BRD4, and …

A base-mediated cascade reaction of CF3-imidoyl sulfoxonium ylides and azo compounds
has been achieved, allowing for facile access to trifluoromethyl-substituted 1, 2 …

The sturdy chelation of 1, 2-diamines and transition-metals would retard or even interrupt the
routine catalytic cycles. In the amidation and asymmetric reductive amination (ARA) cascade …

Photocatalytic dehydrogenative [2+ 2] cycloadditions between amines and alkenes were
developed that allow for the stereoselective and high-yielding synthesis of functionalized …

An enantioselective one‐pot catalytic strategy to dihydroquinoxalinones, featuring novel 1‐
phenylsulfonyl‐1‐cyano enantioenriched epoxides as masked α‐halo acyl halide synthons …

An NHC-catalyzed α-carbon amination of chloroaldehydes was developed. Cyclohexadiene-
1, 2-diimines are used as amination reagents and four-atom synthons. Our reaction affords …

An effective copper-catalyzed direct C–H/N–H cross-coupling of quinoxalin-2 (1H)-ones with
diverse unprotected 2-quinoxalinones and 2-quinolinones has been developed. This …