Regulation of microRNA function in animals
LFR Gebert, IJ MacRae - Nature reviews Molecular cell biology, 2019 - nature.com
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …
key regulators of biological processes in animals. These small RNAs form complex networks …
Nutrients mediate intestinal bacteria–mucosal immune crosstalk
The intestine is the shared site of nutrient digestion, microbiota colonization and immune cell
location and this geographic proximity contributes to a large extent to their interaction. The …
location and this geographic proximity contributes to a large extent to their interaction. The …
Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications
Drug resistance is a major hurdle in cancer treatment and a key cause of poor prognosis.
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
RNA editing, a widespread post-transcriptional mechanism, has emerged as a new player in
cancer biology. Recent studies have reported key roles for individual miRNA editing events …
cancer biology. Recent studies have reported key roles for individual miRNA editing events …
The ability of microRNAs to regulate the immune response in ischemia/reperfusion inflammatory pathways
P Artimovič, I Špaková, E Macejková, T Pribulová… - Genes & …, 2024 - nature.com
MicroRNAs play a crucial role in regulating the immune responses induced by
ischemia/reperfusion injury. Through their ability to modulate gene expression, microRNAs …
ischemia/reperfusion injury. Through their ability to modulate gene expression, microRNAs …
Association between the pig genome and its gut microbiota composition
D Crespo-Piazuelo, L Migura-Garcia, J Estellé… - Scientific reports, 2019 - nature.com
The gut microbiota has been evolving with its host along the time creating a symbiotic
relationship. In this study, we assess the role of the host genome in the modulation of the …
relationship. In this study, we assess the role of the host genome in the modulation of the …
Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets
Abstract A-to-I RNA editing is an important post-transcriptional modification, known to be
altered in tumors. It targets dozens of sites within miRNAs, some of which impact miRNA …
altered in tumors. It targets dozens of sites within miRNAs, some of which impact miRNA …
MiRNAs and inflammatory bowel disease: An interesting new story
Inflammatory bowel disease (IBD), as a chronic and recurrent inflammatory disorder, is
caused by a dysregulated and aberrant immune response to exposed environmental factors …
caused by a dysregulated and aberrant immune response to exposed environmental factors …
The role of A-to-I RNA editing in cancer development
Adenosine-to-inosine (A-to-I) RNA editing is the most common type of post-transcriptional
nucleotide modification in humans, which is catalyzed in ADAR enzymes. Recent genomic …
nucleotide modification in humans, which is catalyzed in ADAR enzymes. Recent genomic …
MicroRNA‐99 family in cancer and immunity
Abstract The microRNA (miR)‐99 family comprising miR‐99a, miR‐99b, and miR‐100 is an
evolutionarily conserved family with existence dating prior to the bilaterians. Members are …
evolutionarily conserved family with existence dating prior to the bilaterians. Members are …