Gut microbiota and cardiovascular disease

M Witkowski, TL Weeks, SL Hazen - Circulation research, 2020 - Am Heart Assoc
Fecal microbial community changes are associated with numerous disease states, including
cardiovascular disease (CVD). However, such data are merely associative. A causal …

Dietary metabolism, the gut microbiome, and heart failure

WHW Tang, DY Li, SL Hazen - Nature Reviews Cardiology, 2019 - nature.com
Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …

[HTML][HTML] TMAO: how gut microbiota contributes to heart failure

Y Zhang, Y Wang, B Ke, J Du - Translational Research, 2021 - Elsevier
An increasing amount of evidence reveals that the gut microbiota is involved in the
pathogenesis and progression of various cardiovascular diseases. In patients with heart …

Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease

JJ Fuster, N Ouchi, N Gokce, K Walsh - Circulation research, 2016 - Am Heart Assoc
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …

Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets

YK Tham, BC Bernardo, JYY Ooi, KL Weeks… - Archives of …, 2015 - Springer
The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Role of cytokines and inflammation in heart function during health and disease

M Bartekova, J Radosinska, M Jelemensky… - Heart failure …, 2018 - Springer
By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various
cytokines have been documented to play important regulatory roles in determining cardiac …

Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and …

Z Förhécz, T Gombos, G Borgulya, Z Pozsonyi… - American heart …, 2009 - Elsevier
OBJECTIVES: The goal of this study was to independently validate the recent observations
on the predictive role of red cell distribution width (RDW) for outcomes in chronic heart …

Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST)

A Deswal, NJ Petersen, AM Feldman, JB Young… - Circulation, 2001 - Am Heart Assoc
Background—Previous reports have shown that elevated circulating levels of cytokines
and/or cytokine receptors predict adverse outcomes in patients with heart failure. However …

Endotoxin and immune activation in chronic heart failure: a prospective cohort study

J Niebauer, HD Volk, M Kemp, M Dominguez… - The Lancet, 1999 - thelancet.com
Background Immune activation in patients with chronic heart failure may be secondary to
endotoxin (lipopolysaccharide) action. We investigated the hypothesis that altered gut …

Are there two types of malnutrition in chronic renal failure? Evidence for relationships between malnutrition, inflammation and atherosclerosis (MIA syndrome)

P Stenvinkel, O Heimbürger, B Lindholm… - Nephrology Dialysis …, 2000 - academic.oup.com
Many methods have been used to assess the presence It is believed that malnutrition is
common in patients with chronic renal failure (CRF). They have reduced of malnutrition in …