Research into the mechanisms and manifestations of solid tumor vascularization was
launched more than 50 years ago with the proposition and experimental demonstrations that …

Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

Prostate cancers are largely unresponsive to immune checkpoint inhibitors (ICIs), and there
is strong evidence that programmed death-ligand 1 (PD-L1) expression itself must be …

Vascular endothelial growth factors (VEGFs) are the key regulators of vasculogenesis in
normal and oncological development. VEGF-A is the most studied angiogenic factor …

Progress in understanding nervous system-cancer interconnections has emphasized the
functional role of semaphorins (SEMAs) and their receptors, neuropilins (NRPs) and plexins …

Immunity has evolved to balance the destructive nature of inflammation with wound healing
to overcome trauma, infection, environmental insults, and rogue malignant cells. The …

Aims The chemotherapy drugs for NSCLC often face the consequences of treatment failure
due to acquired drug resistance. Tumor chemotherapy resistance is often accompanied by …

The high rate of recurrence after radiation therapy in triple-negative breast cancer (TNBC)
indicates that novel approaches and targets are needed to enhance radiosensitivity. Here …

There is a preliminary record suggesting that β2-adrenergic agonists may have therapeutic
value in Parkinson's disease; recent studies have proposed a possible role of these agents …

Abstract Chromobox protein homolog 2 (CBX2) exerts a multifaceted impact on the
progression of aggressive cancers. The proteasome-dependent pathway is crucial for …