Primary human fibroblasts have the remarkable ability to use their nucleus like a piston,
switching from low-to high-pressure protrusions in response to the surrounding three …

Microtubule and actin are the two major cytoskeletal polymers that form organized functional
structures in the interior of eukaryotic cells. Although the structural mechanics of the …

The myosin super-relaxed (SRX) state is central to striated muscle metabolic and functional
regulation. In skeletal muscle, SRX myosin are predominantly colocalized with myosin …

Cytoskeletal filaments, such as microtubules and actin filaments, play important roles in the
mechanical integrity of cells and the ability of cells to respond to their environment …

Septins are a family of eukaryotic guanosine phosphate-binding proteins that form linear
heterooligomeric complexes, which, in turn, polymerize end-on-end into filaments. These …

We are a network of Early Career Researchers (ECRs) and a Project Manager who are
working on UKRI's" Physics of Life" grants which aim to merge ideas and techniques …