Introduction The globus pallidus internus (GPi) region has evolved as a potential target for
deep brain stimulation (DBS) in Parkinson's disease (PD). DBS of the GPi (GPi DBS) is an …

Parkinson's disease (PD) is associated with excessive beta activity in the basal ganglia.
Brain sensing implants aim to leverage this biomarker for demand-dependent adaptive …

Levodopa-induced dyskinesias (LIDs) are a common complication in patients with
Parkinson's disease (PD). A complex cascade of electrophysiological and molecular events …

Background Sleep disturbances are highly prevalent in movement disorders, potentially due
to the malfunctioning of basal ganglia structures. Pallidal deep brain stimulation (DBS) has …

Over the past two decades, animal models of Parkinson's disease (PD) have helped to
determine the plausible underlying mechanism of levo-dihydroxyphenylalanine (l-DOPA) …

The effect of subthalamic nucleus deep brain stimulation (STN-DBS) on balance function in
patients with Parkinson's disease (PD) and the potential outcome predictive factors remains …

There are many documented sex differences in the clinical course, symptom expression
profile, and treatment response of Parkinson's disease, creating additional challenges for …

Background Deep brain stimulation (DBS) is an established therapeutic option in advanced
Parkinson's disease (PD). Literature data and recent guidelines remain inconclusive about …

Time is infinite movement in constant motion. We are glad to see that Neurorestoratology, a
new discipline, has grown into a rich field involving many global researchers in recent years …

Sleep difficulties affect up to 98% of Parkinson's disease (PD) patients and are often not well
treated. How globus pallidus internus (GPi)-DBS could help is less understood. We …