Emerging role of nanocarriers based topical delivery of anti‐fungal agents in combating growing fungal infections

T Waghule, S Sankar, VK Rapalli… - Dermatologic …, 2020 - Wiley Online Library
The incidences of fungal infections have greatly increased over the past few years,
particularly in humid and industrialized areas. The severity of such infections ranges from …

Sesamol-loaded PLGA nanosuspension for accelerating wound healing in diabetic foot ulcer in rats

K Gourishetti, R Keni, PG Nayak, SR Jitta… - International Journal …, 2020 - Taylor & Francis
Background Diabetic foot ulcer is an intractable complication of diabetes, characterized by
the disturbed inflammatory and proliferative phases of wound healing. Sesamol, a phenolic …

A comprehensive literature review of lipids used in the formulation of lipid nanoparticles

I Chauhan, L Singh - Current Nanomaterials, 2023 - ingentaconnect.com
Lipid nanocarriers are reaching new heights in the field of drug delivery. The core of this
technology resides in simple molecules, ie, lipids. Solid and liquid lipids of biocompatible …

Quercetin loaded cationic solid lipid nanoparticles in a mucoadhesive in situ gel—a novel intravesical therapy tackling bladder cancer

S Shawky, S Makled, A Awaad, N Boraie - Pharmaceutics, 2022 - mdpi.com
The study aim was to develop an intravesical delivery system of quercetin for bladder cancer
management in order to improve drug efficacy, attain a controlled release profile and extend …

QbD based antifungal drug-loaded ophthalmic liposomal formulation for the management of fungal keratitis: In vitro, ex vivo and in vivo pharmacokinetic studies

SN Sanap, AC Bisen, A Mishra, A Biswas… - Journal of Drug Delivery …, 2022 - Elsevier
An attempt has been made for controlling the drug release of antifungal drug fluconazole
(FCZ) thereby formulating nanoliposomes (NLs) with increasing residence time by applying …

Enhancing the antifungal activity and ophthalmic transport of fluconazole from PEGylated polycaprolactone loaded nanoparticles

AM Almehmady, KM El-Say, MA Mubarak… - Polymers, 2022 - mdpi.com
Fungal eye infections are caused mainly by an eye injury and can result in serious eye
damage. Fluconazole (FLZ), a broad-spectrum antifungal agent, is a poorly soluble drug …

Mannose-Functionalized Isoniazid-Loaded Nanostructured Lipid Carriers for Pulmonary Delivery: In Vitro Prospects and In Vivo Therapeutic Efficacy Assessment

S Ahalwat, DC Bhatt, S Rohilla, V Jogpal, K Sharma… - Pharmaceuticals, 2023 - mdpi.com
Resistance to isoniazid (INH) is common and increases the possibility of acquiring multidrug-
resistant tuberculosis. For this study, isoniazid-loaded nanostructured lipid carriers (INH …

Fexofenadine-loaded chitosan coated solid lipid nanoparticles (SLNs): A potential oral therapy for ulcerative colitis

WA El-Dakroury, MB Zewail, GF Asaad… - European Journal of …, 2024 - Elsevier
The targeting and mucoadhesive features of chitosan (CS)-linked solid lipid nanoparticles
(SLNs) were exploited to efficiently deliver fexofenadine (FEX) into the colon, forming a …

Nanostructured lipid carriers (NLC)-based gel formulations as etodolac delivery: from gel preparation to permeation study

A Czajkowska-Kośnik, E Szymańska, K Winnicka - Molecules, 2022 - mdpi.com
Topical administration of drug is an attractive alternative to the oral administration as it
provides a reduction in adverse reactions and an enhancement of therapeutic effects. The …

Atorvastatin solid lipid nanoparticles as a promising approach for dermal delivery and an anti-inflammatory agent

SS Shahraeini, J Akbari, M Saeedi… - AAPS …, 2020 - Springer
In the current research, the main focus was to overcome dermal delivery problems of
atorvastatin. To this end, atorvastatin solid lipid nanoparticles (ATR-SLNs) were prepared by …