Endothelial Ca2+ Signaling, Angiogenesis and Vasculogenesis: Just What It Takes to Make a Blood Vessel
It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …
Endothelial Transient Receptor Potential Channels and Vascular Remodeling: Extracellular Ca2 + Entry for Angiogenesis, Arteriogenesis and Vasculogenesis
Vasculogenesis, angiogenesis and arteriogenesis represent three crucial mechanisms
involved in the formation and maintenance of the vascular network in embryonal and post …
involved in the formation and maintenance of the vascular network in embryonal and post …
The molecular heterogeneity of store-operated Ca2+ entry in vascular endothelial cells: the different roles of Orai1 and TRPC1/TRPC4 channels in the transition from …
F Moccia, V Brunetti, A Perna, G Guerra… - International journal of …, 2023 - mdpi.com
Store-operated Ca2+ entry (SOCE) is activated in response to the inositol-1, 4, 5-
trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …
trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …
Conjugated polymers optically regulate the fate of endothelial colony-forming cells
The control of stem and progenitor cell fate is emerging as a compelling urgency for
regenerative medicine. Here, we propose a innovative strategy to gain optical control of …
regenerative medicine. Here, we propose a innovative strategy to gain optical control of …
Intracellular Ca2+ signalling: unexpected new roles for the usual suspect
Cytosolic Ca2+ signals are organized in complex spatial and temporal patterns that underlie
their unique ability to regulate multiple cellular functions. Changes in intracellular Ca2+ …
their unique ability to regulate multiple cellular functions. Changes in intracellular Ca2+ …
[HTML][HTML] Conjugated polymers mediate intracellular Ca2+ signals in circulating endothelial colony forming cells through the reactive oxygen species-dependent …
Endothelial colony forming cells (ECFCs) represent the most suitable cellular substrate to
induce revascularization of ischemic tissues. Recently, optical excitation of the light-sensitive …
induce revascularization of ischemic tissues. Recently, optical excitation of the light-sensitive …
Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome
Background The adult mammalian heart retains residual regenerative capability via
endogenous cardiac progenitor cell (CPC) activation and cardiomyocyte proliferation. We …
endogenous cardiac progenitor cell (CPC) activation and cardiomyocyte proliferation. We …
Endothelial TRPV1 as an emerging molecular target to promote therapeutic angiogenesis
Therapeutic angiogenesis represents an emerging strategy to treat ischemic diseases by
stimulating blood vessel growth to rescue local blood perfusion. Therefore, injured …
stimulating blood vessel growth to rescue local blood perfusion. Therefore, injured …
Therapeutic potential of endothelial colony-forming cells in ischemic disease: strategies to improve their regenerative efficacy
Cardiovascular disease (CVD) comprises a range of major clinical cardiac and circulatory
diseases, which produce immense health and economic burdens worldwide. Currently …
diseases, which produce immense health and economic burdens worldwide. Currently …
Endolysosomal Ca2+ Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind!
The acidic vesicles of the endolysosomal (EL) system are emerging as an intracellular Ca2+
store implicated in the regulation of multiple cellular functions. The EL Ca2+ store releases …
store implicated in the regulation of multiple cellular functions. The EL Ca2+ store releases …