Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Background The cumulative effect of taking multiple medicines with anticholinergic
properties termed as anticholinergic burden can adversely impact cognition, physical …

The NCCN Guidelines for Older Adult Oncology address specific issues related to the
management of cancer in older adults, including screening and comprehensive geriatric …

Objectives: to determine the effect of drugs with anti-cholinergic properties on relevant
health outcomes. Design: electronic published and unpublished literature/trial registries …

The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …

Drugs with anticholinergic action are widely prescribed in the elderly population due to their
potential clinical benefits. However, these benefits are limited by adverse effects which may …

Introduction: Anticholinergics are a class of medicines that block the neurotransmitter,
acetylcholine, in the brain and peripheral tissues. Medicines with anticholinergic activity are …

Background Cumulative anticholinergic exposure (anticholinergic burden) has been linked
to a number of adverse outcomes. To conduct research in this area, an agreed approach to …

Objectives To investigate whether anticholinergic burden scores from nine published
anticholinergic scales are associated with adverse health outcomes, including hospital …

The dramatic demographic changes that are occurring in the third millennium are modifying
the mission of generalist professionals such as primary care physicians and internists …