Owing to its remarkable ease of use, ultrasound has recently been explored for stimulating
or amplifying immune responses during cancer therapy, termed 'sono-immunotherapy' …

Diffuse midline gliomas (DMGs), including diffuse intrinsic pontine glioma, have among the
highest mortality rates of all childhood cancers, despite recent advancements in cancer …

Abstract Diffuse Intrinsic Pontine Glioma (DIPG), now known as Diffuse Midline Glioma
(DMG) is a devastating pediatric brain tumor with limited treatment options and a very poor …

Introduction Histotripsy is a novel focused ultrasound tumor ablation modality with potent
immunostimulatory effects. Methods To measure the spatiotemporal kinetics of local …

The blood–brain barrier (BBB) continues to represent one of the most significant challenges
for successful drug-based treatments of neurological disease. Mechanical modulation of the …

Integrating multimodal neuro-and nanotechnology-enabled precision immunotherapies with
extant systemic immunotherapies may finally provide a significant breakthrough for …

The tumor hypoxic microenvironment is a dynamic status that is closely related to tumor
growth, metastasis, clearance, and recurrence. Hypoxic conditions are present in almost all …

Simple Summary Minimally invasive procedures that directly deliver heat into tumors are
commonly used to treat a wide range of malignancies. In this review, we discuss the …

Craniopharyngiomas (CP) are rare noncancerous brain tumors located in the skull base. To
date, CP remain challenging-to-resect tumors, owing to their difficult location and invasive …

Cancer is a devasting disease resulting in millions of deaths worldwide in both humans and
companion animals, including dogs. Treatment of cancer is complex and challenging and …