Metals and metal alloys are the most used materials in orthopedic implants. The focus is on
total hip arthroplasty (THA) that, though well tolerated, may be associated with local and …

In many biomedical applications, titanium forms an interface with tissues, which is crucial to
ensure its long-term stability and safety. In order to exert control over this process, titanium …

Osteolysis caused by wear debris around the prosthesis is the main reason for aseptic
loosening. Extending prosthetic service life is still challenging. In this study, we first …

Background: Previous epidemiologic studies suggest associations between preterm birth
and ambient air pollution. Objective: We investigated associations between 11 ambient air …

Aseptic loosening of orthopaedic implants is induced by wear particles generated from the
polymeric and metallic components of the implants. Substantial evidence suggests that …

Background Sinomenine (SIN) is an anti-inflammatory drug that has been used for decades
in China to treat arthritis. In a previous study, SIN acted on α7 nicotinic acetylcholine …

Background: Recent studies indicate that females demonstrate an increased risk of
experiencing adverse local tissue reactions, aseptic loosening, and revision after primary …

Cobalt and chromium ions released from cobalt‐chromium‐molybdenum (CoCrMo)‐based
implants are a potential health concern, especially since both ions have been shown to …

Chronic pancreatitis (CP) is a progressive inflammatory disease of the pancreas, leading to
its fibrotic destruction. There are currently no drugs that can stop or slow the progression of …

The alveolar type II epithelial cell, regarded historically as a key target cell in initial injury by
silica, now appears to be important in both defense from lung damage as well as elaboration …