Contributions of Kv3 channels to neuronal excitability

B Rudy, A Chow, D Lau, Y Amarillo… - Annals of the New …, 1999 - Wiley Online Library
Four mammalian Kv3 genes have been identified, each of which generates, by alternative
splicing, multiple protein products differing in their C‐terminal sequence. Products of the …

Optical approaches to embryonic development of neural functions in the brainstem

Y Momose-Sato, K Sato, K Kamino - Progress in neurobiology, 2001 - Elsevier
The ontogenetic approach to physiological events is a useful strategy for understanding the
functional organization/architecture of the vertebrate brainstem. However, conventional …

Spreading depression in human neocortical slices

A Gorji, D Scheller, H Straub, F Tegtmeier, R Köhling… - Brain research, 2001 - Elsevier
Cortical spreading depression (CSD) occurrence has been suggested to be associated with
seizures, migraine aura, head injury and brain ischemia-infarction. Only few studies …

Early development of voltage-gated ion currents and firing properties in neurons of the mouse cerebral cortex

HL Picken Bahrey, WJ Moody - Journal of neurophysiology, 2003 - journals.physiology.org
Voltage-and current-clamp recordings were made from acute slices of mouse cerebral
cortex from embryonic day 14 to postnatal day 17. We targeted cells in the migratory …

Quantification of optical signals with electrophysiological signals in neural activities of Di-4-ANEPPS stained rat hippocampal slices

T Tominaga, Y Tominaga, H Yamada… - Journal of neuroscience …, 2000 - Elsevier
We have quantified the optical signals of synaptically induced neural activities in an in vitro
brain slice preparation in terms of electrophysiological signals. The qualification was done …

α7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in β-amyloid infused rats

L Chen, K Yamada, T Nabeshima, M Sokabe - Neuropharmacology, 2006 - Elsevier
Continuous intracerebroventricular infusion of β-amyloid peptide 1–40 (Aβ (1–40)) in animal
models induces learning and memory impairment associated with dysfunction of the …

Amygdala input promotes spread of excitatory neural activity from perirhinal cortex to the entorhinal–hippocampal circuit

R Kajiwara, I Takashima, Y Mimura… - Journal of …, 2003 - journals.physiology.org
A number of sensory modalities most likely converge in the rat perirhinal cortex. The
perirhinal cortex also interconnects with the amygdala, which plays an important role in …

Changes in mitochondrial function resulting from synaptic activity in the rat hippocampal slice

VP Bindokas, CC Lee, WF Colmers… - Journal of …, 1998 - Soc Neuroscience
Digital imaging microfluorimetry was used to visualize changes in mitochondrial potential
and intracellular Ca2+ concentration,[Ca2+] i, in thick slices of rat hippocampus. Electrical …

Assessing seizure liability in vitro with voltage-sensitive dye imaging in mouse hippocampal slices

Y Utsumi, M Taketoshi, M Miwa, Y Tominaga… - Frontiers in Cellular …, 2023 - frontiersin.org
Non-clinical toxicology is a major cause of drug candidate attrition during development. In
particular, drug-induced seizures are the most common finding in central nervous system …

Optical detection of synaptically induced glutamate transport in hippocampal slices

S Kojima, T Nakamura, T Nidaira… - Journal of …, 1999 - Soc Neuroscience
Although it has long been believed that glial cells play a major role in transmitter uptake at
synapses in the CNS, the relative contribution of glial and neuronal cells to reuptake of …