[HTML][HTML] Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy

J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …

[HTML][HTML] Food anthocyanins: Malvidin and its glycosides as promising antioxidant and anti-inflammatory agents with potential health benefits

A Merecz-Sadowska, P Sitarek, T Kowalczyk, K Zajdel… - Nutrients, 2023 - mdpi.com
Anthocyanins are flavonoid compounds that are abundantly present in fruits and vegetables.
These compounds contribute to the color of these foods and offer various health benefits to …

Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis

HS Tuli, J Kaur, K Vashishth, K Sak, U Sharma… - Archives of …, 2023 - Springer
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …

2D cobalt oxyhydroxide nanozymes inhibit inflammation by targeting the NLRP3 inflammasome

Z Chen, P Chen, Y Zhu, J Qian, X Huang… - Advanced Functional …, 2023 - Wiley Online Library
Nucleotide‐binding domain and leucine rich repeat family pyrin domain containing 3
(NLRP3) inflammasomes are implicated in diverse inflammatory diseases, so their activation …

[HTML][HTML] Focus on the role of the NLRP3 inflammasome in multiple sclerosis: pathogenesis, diagnosis, and therapeutics

Y Cui, H Yu, Z Bu, L Wen, L Yan, J Feng - Frontiers in Molecular …, 2022 - frontiersin.org
Neuroinflammation is initiated with an aberrant innate immune response in the central
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …

Molybdenum and cadmium cause blood–testis barrier dysfunction through ROS-mediated NLRP3 inflammasome activation in sheep

L Jiang, F Yang, H Liao, W Chen, X Dai, C Peng… - Science of the Total …, 2024 - Elsevier
In this study, 24 healthy male sheep were divided into four groups: the control group, Mo
group (45 mg Mo· kg-1· BW), Cd group (1 mg Cd· kg-1· BW), and Mo+ Cd group (45 mg Mo …

[HTML][HTML] Oxidative stress and ROS-mediated cellular events in RSV infection: potential protective roles of antioxidants

X Yang, X Liu, Y Nie, F Zhan, B Zhu - Virology Journal, 2023 - Springer
Respiratory syncytial virus (RSV), a member of the Pneumoviridae family, can cause severe
acute lower respiratory tract infection in infants, young children, immunocompromised …

[HTML][HTML] Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice

J Chen, S Tang, S Ke, JJ Cai, D Osorio, A Golovko… - Redox Biology, 2022 - Elsevier
The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding
RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study …

Ursolic acid alleviates chronic prostatitis via regulating NLRP3 inflammasome‐mediated Caspase‐1/GSDMD pyroptosis pathway

S Liu, B Guo, Q Gao, Y Deng, B Yan… - Phytotherapy …, 2024 - Wiley Online Library
Ursolic acid (UA) is a naturally occurring pentacyclic triterpenoid widely found in fruits and
vegetables. It has been reported that UA has anti‐inflammatory effects. However, its efficacy …

[HTML][HTML] NLRP3 inflammasome as a sensor of micro-and nanoplastics immunotoxicity

A Alijagic, A Hedbrant, A Persson, M Larsson… - Frontiers in …, 2023 - frontiersin.org
Micro-and nanoplastics (MNPs) are emerging pollutants with scarcely investigated effects on
human innate immunity. If they follow a similar course of action as other, more thoroughly …