Human papillomaviruses (HPVs) are small DNA viruses; some oncogenic ones can cause
different types of cancer, in particular cervical cancer. HPV-associated carcinogenesis …

Human papillomavirus (HPV) infection is linked to development of cancer of cervix, vagina,
vulva, penis, ano-genital and non-genital oro-pharyngeal sites. HPV being a sexually …

The present invention relates to chirally controlled oligonucleotides, chirally controlled
oligonucleotide compositions, and the method of making and using the same. The invention …

The present application, among other things, provides technologies, eg, reagents, methods,
etc. for preparing oligonucleotides comprising phosphorothiotriesters linkages, eg …

US9695211B2 - Method for the synthesis of phosphorus atom modified nucleic acids - Google
Patents US9695211B2 - Method for the synthesis of phosphorus atom modified nucleic acids …

Pancreatic cancer is one of the most lethal types of cancer, with aggressive properties
characterized by metastasis, recurrence and drug resistance. Cancer stem cells are …

PR domain zinc finger protein 14 (PRDM14) maintains stemness in embryonic stem cells via
epigenetic mechanisms. Although PRDM14 is elevated in several cancers, it is unclear if …

PRDM14 is highly expressed in several cancers but is not detected in normal tissues. It
confers cancer stem cell‐like properties, including chemoresistance and distant metastasis …

Solution The present invention relates to an adjuvant which com prises oligonucleotides
which comprise two to four sequences each represented by 5'-X, CpG X2-3'and has a length …

Abstract wherein each nucleic acid at 3′ end and 5′ end of the oligonucleotide is S type
nucleic acid connected by phosphorothioate linkage, and wherein the oligonucleotide …