β-Carboline-based molecular hybrids as anticancer agents: A brief sketch

JP Soni, Y Yeole, N Shankaraiah - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
Cancer is a huge burden on the healthcare system and is foremost cause of mortality across
the globe. Among various therapeutic strategies, chemotherapy plays an enormous role in …

A review on new natural and synthetic anti-leishmanial chemotherapeutic agents and current perspective of treatment approaches.

N Majumder, A Banerjee, S Saha - Acta Tropica, 2023 - Elsevier
Leishmaniases are considered among the most neglected yet dangerous parasitic diseases
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …

AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro

LC Saramago, MV Santana, BF Gomes… - Journal of Chemical …, 2023 - ACS Publications
SARS-CoV-2 is the causative agent of COVID-19 and is responsible for the current global
pandemic. The viral genome contains 5 major open reading frames of which the largest …

Synthesis of Tetrahydro-β-carboline Derivatives under Electrochemical Conditions in Deep Eutectic Solvents

MO Mousa, ME Adly, AM Mahmoud, HB El-Nassan - ACS omega, 2024 - ACS Publications
In this work, a novel, green, and atom-efficient method for the synthesis of tetrahydro-β-
carboline derivatives using electrochemistry (EC) in deep eutectic solvents (DESs) was …

Amino acid containing amphiphilic hydrogelators with antibacterial and antiparasitic activities

B Mondal, VK Gupta, B Hansda, A Bhoumik, T Mondal… - Soft Matter, 2022 - pubs.rsc.org
Nanoscale self-assembly of peptide constructs represents a promising means to present
bioactive motifs to develop new functional materials. Here, we present a series of peptide …

[HTML][HTML] Beta-carboline as a promising heterocyclic nucleus: Synthetic aspects, pharmacological potential and structure activity relationship

M Thatikayala, P Wadhwa, P Kaur, PK Singh… - European Journal of …, 2022 - Elsevier
Beta-carboline is an indole alkaloid which has been identified as a valuable heterocyclic
nucleus in the field of medicinal chemistry. It has different biological activities like …

An updates: Oxidative aromatization of THβC to β-carbolines and their application for the β-carboline alkaloids synthesis

S Gaikwad, L Kováčiková, P Pawar, M Gaikwad… - Tetrahedron, 2024 - Elsevier
This review is an informative and constructive resource for researchers interested in the
synthesis of β-carbolines. It provides a comprehensive overview of the various synthetic …

DIPEA‐Assisted Efficient One‐Pot Three‐Component Synthesis of Novel β‐Carboline Tethered Pyran Derivatives

N Banyal, CC Malakar, R Kumar, V Singh - ChemistrySelect, 2024 - Wiley Online Library
A potential DIPEA‐assisted approach has been unfolded for the synthesis of novel β‐
carboline tethered‐4H‐pyran derivatives via one‐pot condensation of 1‐formyl‐9H‐β …

Design, synthesis and evaluation of novel β-carboline ester analogues as potential anti-leishmanial agents

B Karan Kumar, Faheem, R Balana Fouce… - Journal of …, 2022 - Taylor & Francis
Leishmaniasis is one of today's most neglected diseases. The emergence of new anti-
leishmanial therapies emphasizes several study groups funded by the World Health …

[HTML][HTML] Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania

SSC Oliveira, CSF Marques, DP de Sousa… - Biochimie, 2021 - Elsevier
Leishmaniasis is a neglected parasitic disease for which the conventional treatment can be
considered inefficient and extremely aggressive, generating several and severe side effects …