[HTML][HTML] The role of NF-κB in breast cancer initiation, growth, metastasis, and resistance to chemotherapy
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …
[HTML][HTML] Role of interferon-gamma (IFN-γ) and IFN-γ receptor 1/2 (IFNγR1/2) in regulation of immunity, infection, and cancer development: IFN-γ-dependent or …
H Ding, G Wang, Z Yu, H Sun, L Wang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
IFN-γ, a soluble cytokine being produced by T lymphocytes, macrophages, mucosal
epithelial cells, or natural killer cells, is able to bind to the IFN-γ receptor (IFNγR) and in turn …
epithelial cells, or natural killer cells, is able to bind to the IFN-γ receptor (IFNγR) and in turn …
Tumor microenvironmental plasmacytoid dendritic cells contribute to breast cancer lymph node metastasis via CXCR4/SDF-1 axis
R Gadalla, H Hassan, SA Ibrahim, MS Abdullah… - Breast cancer research …, 2019 - Springer
Abstract Purpose Plasmacytoid dendritic cells (PDCs) infiltration into breast cancer tissues is
associated with poor prognosis. Also, CXCR4 shows compelling evidences to be exploited …
associated with poor prognosis. Also, CXCR4 shows compelling evidences to be exploited …
CC chemokine receptor 7 in cancer
CA Bill, CM Allen, CM Vines - Cells, 2022 - mdpi.com
CC chemokine receptor 7 (CCR7) was one of the first two chemokine receptors that were
found to be upregulated in breast cancers. Chemokine receptors promote chemotaxis of …
found to be upregulated in breast cancers. Chemokine receptors promote chemotaxis of …
Energy metabolism, metabolite, and inflammatory profiles in human ex vivo adipose tissue are influenced by obesity status, metabolic dysfunction, and treatment …
Simple Summary Oesophageal adenocarcinoma (OAC) is a poor prognosis cancer with
limited response rates to current treatment modalities and is strongly linked to obesity status …
limited response rates to current treatment modalities and is strongly linked to obesity status …
[HTML][HTML] High expression of CCR7 predicts lymph node metastasis and good prognosis in triple negative breast cancer
X Li, S Sun, N Li, J Gao, J Yu, J Zhao, M Li… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Previous preclinical and clinical studies have reported a positive
correlation between the expression of the CC chemokine receptor 7 (CCR7) and the …
correlation between the expression of the CC chemokine receptor 7 (CCR7) and the …
[HTML][HTML] Silencing of CCR7 inhibits the growth, invasion and migration of prostate cancer cells induced by VEGFC
BJ Chi, CL Du, YF Fu, YN Zhang… - International journal of …, 2015 - ncbi.nlm.nih.gov
Early in prostate cancer development, tumor cells express vascular endothelial growth factor
C (VEGF-C), a secreted molecule that is important in angiogenesis progression. CC …
C (VEGF-C), a secreted molecule that is important in angiogenesis progression. CC …
Inflammatory and non-inflammatory breast cancer: a potential role for detection of multiple viral DNAs in disease progression
M El-Shinawi, HT Mohamed, HH Abdel-Fattah… - Annals of surgical …, 2016 - Springer
Background Inflammatory breast cancer (IBC) is the most lethal form of breast cancer.
Multiple viral infections in IBC tissues were found to be associated with disease …
Multiple viral infections in IBC tissues were found to be associated with disease …
Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors
P Weitzenfeld, O Kossover, C Körner… - Journal of Leucocyte …, 2016 - academic.oup.com
Chemokine axes have been shown to mediate site-specific metastasis in breast cancer, but
their relevance to different subtypes has been hardly addressed. Here, with the focus on the …
their relevance to different subtypes has been hardly addressed. Here, with the focus on the …
DNA methylation‐mediated silencing of microRNA‐204 enhances T cell acute lymphoblastic leukemia by up‐regulating MMP‐2 and MMP‐9 via NF‐κB
C Lin, D Chen, T Xiao, D Lin, D Lin, L Lin… - Journal of Cellular …, 2021 - Wiley Online Library
T cell acute lymphoblastic leukaemia (T‐ALL) is a highly aggressive haematological cancer
of the bone marrow. The abnormal expression of microRNAs (miRNAs) is reportedly …
of the bone marrow. The abnormal expression of microRNAs (miRNAs) is reportedly …