Realizing the clinical utility of saliva for monitoring oral diseases

JL Ebersole, H Hasturk, M Huber… - Periodontology …, 2024 - Wiley Online Library
In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …

Diagnostic potential and future directions of biomarkers in gingival crevicular fluid and saliva of periodontal diseases: Review of the current evidence

NA Ghallab - Archives of oral biology, 2018 - Elsevier
Objectives The holy grail of biomarker research in periodontology is to develop a high
impact diagnostics which have a significant impact on clinical decision-making, patient …

Biological markers for pulpal inflammation: a systematic review

DK Rechenberg, JC Galicia, OA Peters - PloS one, 2016 - journals.plos.org
Background and Objective Pulpitis is mainly caused by an opportunistic infection of the pulp
space with commensal oral microorganisms. Depending on the state of inflammation …

Estimation of salivary tumor necrosis factor-alpha in chronic and aggressive periodontitis patients

SS Varghese, H Thomas, ND Jayakumar… - Contemporary clinical …, 2015 - journals.lww.com
Objective: The aim of the study is to estimate the salivary TNF-α in chronic and aggressive
periodontitis and control participants and further correlate the levels with clinical parameter …

Targeted salivary biomarkers for discrimination of periodontal health and disease (s)

JL Ebersole, R Nagarajan, D Akers… - Frontiers in cellular and …, 2015 - frontiersin.org
Generally, clinical parameters are used in dental practice for periodontal disease, yet
several drawbacks exist with the clinical standards for addressing the needs of the public at …

Use of IL‐1 β, IL‐6, TNF‐α, and MMP‐8 biomarkers to distinguish peri‐implant diseases: a systematic review and meta‐analysis

I Ghassib, Z Chen, J Zhu… - Clinical implant dentistry …, 2019 - Wiley Online Library
Objective To investigate the use of peri‐implant crevicular fluid (PICF) interleukin‐1β (IL‐1β),
IL‐6, tumor necrosis factor‐α (TNF‐α), and matrix metalloproteinase‐8 (MMP‐8) biomarkers …

Salivary biomarkers of periodontal disease in response to treatment

WM Sexton, Y Lin, RJ Kryscio… - Journal of clinical …, 2011 - Wiley Online Library
Sexton WM, Lin Y, Kryscio RJ, Dawson III DR, Ebersole JL, Miller CS. Salivary biomarkers of
periodontal disease in response to treatment. J Clin Periodontol 2011; 38: 434–441. doi …

Saliva/pathogen biomarker signatures and periodontal disease progression

JS Kinney, T Morelli, T Braun… - Journal of dental …, 2011 - journals.sagepub.com
The purpose of this study was to determine the role of saliva-derived biomarkers and
periodontal pathogens during periodontal disease progression (PDP). One hundred human …

A bibliometric analysis of Periodontology 2000

P Ahmad, JA Asif, MK Alam, J Slots - Periodontology 2000, 2020 - Wiley Online Library
The continually high impact factor of Periodontology 2000 (7.861 for 2018), the level of
which is unprecedented among dental journals, prompted the present bibliometric analysis …

Periodontal disease immunology:'double indemnity'in protecting the host

JL Ebersole, DR Dawson III, LA Morford… - Periodontology …, 2013 - Wiley Online Library
During the last two to three decades our understanding of the immunobiology of periodontal
disease has increased exponentially, both with respect to the microbial agents triggering the …