BACKGROUND The placenta is the active interface between mother and foetus, bearing the
molecular marks of rapid development and exposures in utero. The placenta is routinely …

Background The placenta acts as a buffer to regulate the degree of fetal exposure to
maternal cortisol through the 11-Beta Hydroxysteroid Dehydrogenase isoenzyme type 2 (11 …

Background The placenta plays an important role in the modulation of pregnancy immunity;
however, there is no consensus regarding the existence of a placental microbiome in …

Introduction Preeclampsia is a maternal hypertensive disorder with uncertain etiology and a
leading cause of maternal and fetal mortality worldwide, causing nearly 40% of premature …

Early pregnancy is characterized by a series of complex and tightly regulated events to
ultimately establish implantation and early placental development. One of the key events is …

The placenta is the essential organ of mammalian pregnancy and errors in its development
and function are associated with a wide range of human pathologies of pregnancy. Genome …

Although fibrosis is one of the most prominent pathologic features of preeclamptic (PE)
placentas, its mechanism remains largely unknown. Consistent with previous reports, we …

While the developing fetus is largely shielded from the external environment through the
protective barrier provided by the placenta, it is increasingly appreciated that environmental …

Aims Gestational diabetes mellitus (GDM) can lead to short-and long-term complications for
the child. Epigenetic alterations could contribute to explaining the metabolic disturbances …

The impact of placental dysfunction and placental injury on the fetus and newborn infant has
become a topic of growing interest in neonatal disease research. However, the use of …