International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Diabetic cardiomyopathy: molecular mechanisms, detrimental effects of conventional treatment, and beneficial effects of natural therapy

B Parim, VV Sathibabu Uddandrao, G Saravanan - Heart Failure Reviews, 2019 - Springer
Diabetic complications are among the largely exigent health problems currently.
Cardiovascular complications, including diabetic cardiomyopathy (DCM), account for more …

Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …

Nicotinamide attenuates streptozotocin-induced diabetes complications and increases survival rate in rats: role of autonomic nervous system

PL Cruz, IC Moraes-Silva, AA Ribeiro, JF Machi… - BMC Endocrine …, 2021 - Springer
Background To evaluate the effect of nicotinamide prior to streptozotocin-induced (STZ)
diabetes in baroreflex sensitivity and cardiovascular autonomic modulation, and its …

From the distinctive smell to therapeutic effects: Garlic for cardiovascular, hepatic, gut, diabetes and chronic kidney disease

M Ribeiro, L Alvarenga, LFMF Cardozo, TR Chermut… - Clinical Nutrition, 2021 - Elsevier
Garlic, a member of the Allium family, widely used in cooking for many centuries, displays
well described antioxidant and anti-inflammatory properties, as a result of its constituent …

Restorative potentiality of S-allylcysteine against diabetic nephropathy through attenuation of oxidative stress and inflammation in streptozotocin–nicotinamide …

VV Sathibabu Uddandrao, P Brahmanaidu… - European journal of …, 2019 - Springer
Aim In the present study, we evaluated the therapeutic potentiality of S-allylcysteine (SAC) in
streptozotocin (STZ)–nicotinamide (NAD)-induced diabetic nephropathy (DN) in …

[HTML][HTML] Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy

GJ Dugbartey, KK Alornyo, BB N'guessan… - Biomedicine & …, 2022 - Elsevier
Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease.
Current pharmacological interventions only retard DN progression. Alpha-lipoic acid (ALA) …

Polyherbal formulation ameliorates diabetic cardiomyopathy through attenuation of cardiac inflammation and oxidative stress via NF-κB/Nrf-2/HO-1 pathway in …

VVS Uddandrao, B Parim, S Singaravel… - Journal of …, 2022 - journals.lww.com
The present study was intended to evaluate the effect of polyherbal formulation (PHF) made
with 3 nutraceuticals, such as Piper nigrum, Terminalia paniculata, and Bauhinia purpurea …

Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague–Dawley rats

P Rameshreddy, VVS Uddandrao… - Molecular and cellular …, 2018 - Springer
The present study evaluated the effects of asiatic acid (AA), a pentacyclic triterpenoid from
Centella asiatica on lipid metabolism parameters in a rat model of obesity induced using a …

Therapeutic role of Azadirachta indica leaves ethanolic extract against diabetic nephropathy in rats neonatally induced by streptozotocin

AEFBM El-Beltagy, AMB Saleh, A Attaallah… - Ultrastructural …, 2021 - Taylor & Francis
Diabetic nephropathy (DN) is manifested by chronic loss of renal function due to damage of
glomeruli and renal tubules. Therefore, this study is mainly designed to evaluate the …