HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …

Vortioxetine, a novel antidepressant for the treatment of major depressive disorder (MDD), is
a 5-HT 3, 5-HT 7 and 5-HT 1D receptor antagonist, 5-HT 1B receptor partial agonist, 5-HT …

Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …

Serotonin regulates many physiological processes including sleep, appetite, and mood.
Thus, serotonergic system is an important target in the treatment of psychiatric disorders …

Being different multifactorial forms of psychopathology, aggression, depression and suicidal
behavior, which is considered to be violent aggression directed against the self, have …

Serotonin modulates several physiological and cognitive pathways throughout the human
body that affect emotions, memory, sleep, and thermal regulation. The complex nature of the …

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized
by repetitive and stereotyped behaviors as well as difficulties with social interaction and …

Introduction: Vortioxetine is a novel antidepressant drug approved for the treatment of major
depressive disorder (MDD) in adults. It is formulated into tablets and has a dose range of 5 …

Summary Serotonin (5‐hydroxytryptamine or 5‐HT) is an important neurotransmitter
regulating a wide range of physiological and pathological functions via activation of …

Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …