Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Melanins are pigment molecules that determine the skin, eye, and hair color of the human
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …

Metalloenzymes are central to a wide range of essential biological activities, including
nucleic acid modification, protein degradation, and many others. The role of metalloenzymes …

Controlling unwanted hyperpigmentation is a major challenge in dermatology and
cosmetology, and safe and efficacious antimelanogenic agents are deemed useful for this …

Copper is an essential trace element in living systems, present in the parts per million
concentration range. It is a key cofactor in a diverse array of biological oxidation-reduction …

Cutaneous melanin pigment plays a critical role in camouflage, mimicry, social
communication, and protection against harmful effects of solar radiation. Melanogenesis is …

Skin‐lightening products are commercially available for cosmetic purposes to obtain lighter
skin complexion. Clinically, they are also used for treatment of hyperpigmentary disorders …

Oculocutaneous albinism (OCA) is a group of inherited disorders of melanin biosynthesis
characterized by a generalized reduction in pigmentation of hair, skin and eyes. The …

This volume covers all aspects of melanin pigmentation, providing a concise,
comprehensive picture of new knowledge gained at the frontiers of research. It draws …

Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human
skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in …