Piperidine derivatives: recent advances in synthesis and pharmacological applications

NA Frolov, AN Vereshchagin - International Journal of Molecular Sciences, 2023 - mdpi.com
Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …

Multicomponent reactions as a potent tool for the synthesis of benzodiazepines

H Farhid, V Khodkari, MT Nazeri… - Organic & …, 2021 - pubs.rsc.org
Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

Green synthesis of CuFe2O4 nanoparticles mediated by Morus alba L. leaf extract: Crystal structure, grain morphology, particle size, magnetic and catalytic properties …

AH Cahyana, AR Liandi, Y Yulizar, Y Romdoni… - Ceramics …, 2021 - Elsevier
Abstract Copper ferrite (CuFe 2 O 4) is one of the most popular ferrite spinel semiconductors
due to its superparamagnetic properties. In this study, CuFe 2 O 4 nanoparticles were …

Electron deficient borane-mediated hydride abstraction in amines: stoichiometric and catalytic processes

S Basak, L Winfrey, BA Kustiana, RL Melen… - Chemical Society …, 2021 - pubs.rsc.org
The manipulation of amino C–H bonds has garnered significant interest from the synthetic
community due to its inherently high atom, step and redox economy. This Tutorial Review …

Multicomponent reactions for the synthesis of active pharmaceutical ingredients

Á Cores, J Clerigué, E Orocio-Rodríguez… - Pharmaceuticals, 2022 - mdpi.com
Multicomponent reactions 9i. e., those that engage three or more starting materials to form a
product that contains significant fragments of all of them), have been widely employed in the …

Multicomponent reaction-assisted drug discovery: A time-and cost-effective green approach speeding up identification and optimization of anticancer drugs

G Graziano, A Stefanachi, M Contino… - International Journal of …, 2023 - mdpi.com
Multicomponent reactions (MCRs) have emerged as a powerful strategy in synthetic organic
chemistry due to their widespread applications in drug discovery and development. MCRs …

Design, synthesis, and structure–activity relationship studies of magnolol derivatives as antifungal agents

H Li, YH He, YM Hu, QR Chu, YJ Chen… - Journal of Agricultural …, 2021 - ACS Publications
Plant pathogenic fungi seriously affect agricultural production and are difficult to control. The
discovery of new leads based on natural products is an important way to innovate …

Ionically tagged magnetic nanoparticles with urea linkers: application for preparation of 2-aryl-quinoline-4-carboxylic acids via an anomeric-based oxidation …

P Ghasemi, M Yarie, MA Zolfigol, AA Taherpour… - ACS …, 2020 - ACS Publications
In this exploration, we reported the design and synthesis of a novel ionically tagged
magnetic nanoparticles bearing urea linkers, namely, Fe3O4@ SiO2@(CH2) 3–urea …

[HTML][HTML] Value-added synthesized acidic polymer nanocomposite with waste chicken eggshell: A novel metal-free and heterogeneous catalyst for Mannich and …

F Bakhshi, G Bagherzade - Arabian Journal of Chemistry, 2023 - Elsevier
The removal of metals from chemical reactions has raised growing concerns for conserving
natural resources and environmental safety. Therefore, it is necessary to expand simple …

How and why to investigate multicomponent reactions mechanisms? A critical review

MO Rodrigues, MN Eberlin, BAD Neto - The Chemical Record, 2021 - Wiley Online Library
We review the most innovative efforts and greatest challenges faced when elucidating
multicomponent reactions (MCRs) mechanisms. When compared to traditional reactions, the …