Background Despite evidence supporting its use, many Enhanced Recovery After Surgery
(ERAS) recommendations remain poorly adhered to and barriers to ERAS implementation …

Eine der größten Limitationen in der Anwendung von Lokalanästhetika liegt in ihrer
begrenzten Wirkdauer. In den letzten Jahren wurden liposomale Formulierungen mit …

Importance Liposomal bupivacaine for pain relief is purported to last 3 days compared with 8
hours with standard bupivacaine. However, its effectiveness is unknown in truncal incisions …

The major limitation of traditional local anesthetics is the finite duration of a single injection.
The present study developed two kinds of novel injectable anesthetic nanocomposites …

Purpose Dexmedetomidine and ketamine may be administered intraoperatively as
continuous infusions to provide opioid-sparing anesthesia. Recent evidence has yielded …

Liposomal bupivacaine (LB) has consistently been considered a potential analgesic for
surgical wound infiltration. However, the evidence of its analgesic effectiveness remains …

Background Despite the extensive administration of the enhanced recovery after surgery
(ERAS) program, postoperative pain remains a major concern for patients. Transversus …

Rationale: To meet the need of long-acting analgesia in postoperative pain management,
slow-releasing formulations of local anesthetics (LAs) have been extensively investigated …

Background: Regional analgesia, such as intercostal nerve blockade (INB), is a viable
modality for postoperative pain control in thoracic surgery patients. Asian patients have …

Background To evaluate whether incisional infiltration of liposomal bupivacaine would
decrease opioid requirement and pain scores after midline vertical laparotomy for suspected …