Inflammation and resolution in obesity

M Soták, M Clark, BE Suur, E Börgeson - Nature Reviews …, 2024 - nature.com
Inflammation is an essential physiological defence mechanism, but prolonged or excessive
inflammation can cause disease. Indeed, unresolved systemic and adipose tissue …

[HTML][HTML] A single extraction 96-well method for LC-MS/MS quantification of urinary eicosanoids, steroids and drugs

J Sieminska, J Kolmert, J Zurita, K Benkestock… - Prostaglandins & Other …, 2024 - Elsevier
Urinary eicosanoid concentrations reflect inflammatory processes in multiple diseases and
have been used as biomarkers of disease as well as suggested for patient stratification in …

Towards better models for studying human adipocytes in vitro

F Baganha, R Schipper, CE Hagberg - Adipocyte, 2022 - Taylor & Francis
With obesity and its comorbidities continuing to rise, we urgently need to improve our
understanding of what mechanisms trigger the white adipose tissue to become dysfunctional …

Attenuation of adipose tissue inflammation by pro-resolving lipid mediators

M Clark, BE Suur, M Soták, E Börgeson - Current Opinion in Endocrine and …, 2024 - Elsevier
Adipose tissue inflammation drives systemic pathophysiology, for instance, obesity-related
cardiometabolic disease. Specialized pro-resolving lipid mediators are a superfamily of …

Combined loss of obscurin and obscurin-like 1 in murine hearts results in impaired diastolic dysfunction, altered metabolism and deregulated mitophagy

K Fujita, P Desmond, J Blondelle, M Soták, MR Rajan… - bioRxiv, 2022 - biorxiv.org
Muscle proteins of the obscurin protein family play important roles in sarcomere
organization, sarcoplasmic reticulum (SR) and T-tubule architecture and function. However …

Promising Anti-Inflammatory Tools: Biomedical Efficacy of Lipoxins and Their Synthetic Pathways

J Chi, J Cheng, S Wang, C Li, M Chen - International Journal of Molecular …, 2023 - mdpi.com
Lipoxins (LXs) have attracted widespread attention as a class of anti-inflammatory lipid
mediators that are produced endogenously by the organism. LXs are arachidonic acid …