First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients

Z Hasanshahi, A Hashempour, F Ghasabi… - Bmc …, 2021 - Springer
Abstract Background NS5A and NS5B proteins of hepatitis C virus (HCV) are the main
targets of compounds that directly inhibit HCV infections. However, the emergence of …

[HTML][HTML] Screening and identification of bioactive compounds from citrus against non-structural protein 3 protease of hepatitis C virus genotype 3a by fluorescence …

M Khan, W Rauf, M Rahman, M Iqbal - World Journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Hepatitis C virus genotype 3a (HCV G3a) is highly prevalent in Pakistan.
Due to the elevated cost of available Food and Drug Administration-approved drugs against …

Hesperidin identified from Citrus extracts potently inhibits HCV genotype 3a NS3 protease

M Khan, W Rauf, F Habib, M Rahman, S Iqbal… - … Medicine and Therapies, 2022 - Springer
Background Hepatitis C virus infection is the main cause of liver ailments across the globe.
Several HCV genotypes have been identified in different parts of the world. Effective drugs …

Characterization of the multidrug efflux transporter styMdtM from Salmonella enterica serovar Typhi

A Shaheen, F Ismat, M Iqbal, A Haque… - Proteins: Structure …, 2021 - Wiley Online Library
Salmonellae are foodborne pathogens and the major cause of gastroenteritis in humans.
Salmonellae express multidrug efflux transporters that play a key role in their drug …

[PDF][PDF] Characterization of the multidrug efflux transporter styMdtM

A Shaheen, F Ismat, M Iqbal, A Haque, Z Ul-Haq… - academia.edu
Salmonellae are foodborne pathogens and the major cause of gastroenteritis in humans.
Salmonellae express multidrug efflux transporters that play a key role in their drug …

[PDF][PDF] Markers of HCV-Related HCC in Egyptian Patients

D ElShennawy, NTA Fouad, H Amer… - Int. J. Curr. Microbiol …, 2016 - academia.edu
Hepatocellular carcinoma (HCC) is the fifth most common cancer, and the second most
common digestive system malignant tumor worldwide, accounting for 5% of all cancers (1 …

[PDF][PDF] The dysregulation of lipid metabolism caused by hepatitis C virus

C Burch - 2017 - researchgate.net
The life cycle of HCV involves a dysregulation in host lipid metabolism that may precede
metabolic complications such as insulin resistance (IR), type 2 diabetes mellitus (T2DM) …