[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
Arachidonic acid metabolism and kidney inflammation
As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …
component of the cell membrane lipid content, is mainly metabolized by three kinds of …
The biosynthesis of enzymatically oxidized lipids
AA Hajeyah, WJ Griffiths, Y Wang, AJ Finch… - Frontiers in …, 2020 - frontiersin.org
Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …
signaling mediators and hormones, regulating various cellular and physiological processes …
Cannabinoids and cytochrome P450 interactions
O Zendulka, G Dovrtelova, K Nosková… - Current drug …, 2016 - ingentaconnect.com
Objective: This review consists of three parts, representing three different possibilities of
interactions between cannabinoid receptor ligands of both exogenous and endogenous …
interactions between cannabinoid receptor ligands of both exogenous and endogenous …
The endocannabinoid system and pain
J Guindon, AG Hohmann - CNS & Neurological Disorders-Drug …, 2009 - ingentaconnect.com
The therapeutic potential of cannabinoids has been the topic of extensive investigation
following the discovery of cannabinoid receptors and their endogenous ligands …
following the discovery of cannabinoid receptors and their endogenous ligands …
Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism
AA Spector, HY Kim - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2015 - Elsevier
Polyunsaturated fatty acids (PUFA) are oxidized by cytochrome P450 epoxygenases to
PUFA epoxides which function as potent lipid mediators. The major metabolic pathways of …
PUFA epoxides which function as potent lipid mediators. The major metabolic pathways of …
Arachidonic acid cytochrome P450 epoxygenase pathway
AA Spector - Journal of lipid research, 2009 - ASBMB
Cytochrome P450 (CYP) epoxygenases convert arachidonic acid to four
epoxyeicosatrienoic acid (EET) regioisomers, 5, 6-, 8, 9-, 11, 12-, and 14, 15-EET, that …
epoxyeicosatrienoic acid (EET) regioisomers, 5, 6-, 8, 9-, 11, 12-, and 14, 15-EET, that …
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites
C Turcotte, F Chouinard, JS Lefebvre… - Journal of Leucocyte …, 2015 - academic.oup.com
Arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA) are endocannabinoids
that have been implicated in many physiologic disorders, including obesity, metabolic …
that have been implicated in many physiologic disorders, including obesity, metabolic …
Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling …
CA Rouzer, LJ Marnett - Chemical reviews, 2011 - ACS Publications
The discovery of the cannabinoid receptors CB1 and CB2 in 19881, 2 and 1990, 3
respectively, and of the endogenous cannabinoid ligands (endocannabinoids) …
respectively, and of the endogenous cannabinoid ligands (endocannabinoids) …
The role of CYP3A in health and disease
LS Klyushova, ML Perepechaeva, AY Grishanova - Biomedicines, 2022 - mdpi.com
CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …