Background: Frontotemporal dementia (FTD) describes a cluster of neurocognitive
syndromes that present with impairment of executive functioning, changes in behavior, and …

In this work, we review clinical features and genetic diagnosis of diseases caused by
mutations in the gene encoding valosin-containing protein (VCP/p97), the functionally …

The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed
since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal …

Mutations in valosin‐containing protein (VCP), an ATPase involved in protein degradation
and autophagy, cause VCP disease, a progressive autosomal dominant adult onset …

Inclusion body myopathy (IBM) associated with Paget disease of the bone (PDB) and
frontotemporal dementia (FTD)(now called IBMPFD), is a progressive autosomal dominant …

Mutations in valosin-containing protein (VCP) cause inclusion body myopathy (IBM)
associated with Paget's disease of the bone (PDB) and fronto-temporal dementia (FTD) or …

Inclusion body myopathy associated with Paget's disease of bone and frontotemporal
dementia (IBMPFD) is a dominantly inherited degenerative disorder caused by mutations in …

The AAA+ ATPase valosin containing protein (VCP) is essential for cell and organ
homeostasis, especially in cells of the nervous system. As part of a large network, VCP …

A number of neurodegenerative diseases have been linked to mutations in the human
protein p97, an abundant cytosolic AAA+ (A TPase a ssociated with various cellular a …

Inclusion body myopathy with Paget disease of the bone (PDB) and/or frontotemporal
dementia (IBMPFD, OMIM 167320), is a progressive autosomal dominant disorder caused …