Abstract Interleukin-6 (IL-6) is a key immunomodulatory cytokine that affects the
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …

Therapeutic options for the highly pathogenic human severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) causing the current pandemic coronavirus disease (COVID …

Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection-
induced inflammatory responses are largely responsible for the death of novel coronavirus …

To fight the Covid-19 pandemic caused by the RNA virus SARS-CoV-2 a global vaccination
campaign is in progress to achieve the immunization of billions of people mainly with …

Abstract Background Angiotensin receptor blockers (ARBs), such as telmisartan, have been
postulated to treat Covid-19-induced lung inflammation. Methods This is a parallel-group …

Microvascular thrombosis is associated with multiorgan failure and mortality in coronavirus
disease 2019 (COVID-19). Although thrombotic complications may be ascribed to the ability …

Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …

The release of interleukin (IL)-6 is stimulated by antigenic peptides from pathogens as well
as by immune cells for activating aggressive inflammation. IL-6 inducing peptides are …

Background and Aims COVID-19 is associated with liver injury and elevated interleukin-6 (IL-
6). We hypothesized that IL-6 trans-signaling in liver sinusoidal endothelial cells (LSECs) …

The outcome of infection is dependent on the ability of viruses to manipulate the infected cell
to evade immunity, and the ability of the immune response to overcome this evasion …