Therapeutic Candidates for Alzheimer's Disease: Saponins

R Zhang, M Zeng, X Zhang, Y Zheng, N Lv… - International Journal of …, 2023 - mdpi.com
Drug development for Alzheimer's disease, the leading cause of dementia, has been a long-
standing challenge. Saponins, which are steroid or triterpenoid glycosides with various …

Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose

HH Kang, AH Naing, CK Kim - Biology, 2020 - mdpi.com
Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …

New naphthalene derivative for cost-effective AChE inhibitors for Alzheimer's treatment: In silico identification, in vitro and in vivo validation

F Anwar, U Saleem, B Ahmad, M Ashraf… - … Biology and Chemistry, 2020 - Elsevier
Neurodegenerative diseases have complex etiology and pose a challenge to scientists to
develop simple and cost-effective synthetic compounds as potential drug candidates for …

Isolation of Antidiabetic Withanolides from Withania coagulans Dunal and Their In Vitro and In Silico Validation

S Maher, MI Choudhary, F Saleem, S Rasheed… - Biology, 2020 - mdpi.com
Withania coagulans (W. coagulans) is well-known in herbal medicinal systems for its high
biological potential. Different parts of the plant are used against insomnia, liver …

Green Synthesis of Withania coagulans Extract-Mediated Zinc Oxide Nanoparticles as Photocatalysts and Biological Agents

S Maher, B Zamina, M Riaz, S Riaz, N Khalid… - ACS …, 2023 - ACS Publications
Recently, biosynthesized nanoparticles (NPs) have played a vital role as an alternative to
physical and chemical methods. Here, a distinctive bioinspired synthesis of zinc oxide …

[HTML][HTML] Anti-Alzheimer's disease molecular mechanism of acori tatarinowii rhizoma based on network pharmacology

Y Zhang, Y Wu, Y Fu, L Lin, Y Lin… - … Science Monitor Basic …, 2020 - ncbi.nlm.nih.gov
Background Acori Tatarinowii Rhizoma (ATR), a traditional Chinese herbal medicine, is
used to treat Alzheimer's disease (AD), which is a worldwide degenerative brain disease …

Physicochemical screening; identification of anticancer, antibacterial and antioxidant principles by fractionation and GC-MS profiling of fruits of Guaiacum officinale L.

S Shoukat - Pakistan Journal of Science, 2021 - pjosr.com
The present work is an attempt to find out biological potential of various extracts and ethanol
fractions of Guaiacum officinale L. Sequential extraction was performed with different …