The role of acute kidney injury in chronic kidney disease

RK Hsu, CY Hsu - Seminars in nephrology, 2016 - Elsevier
There is increasing recognition that acute kidney injury (AKI) and chronic kidney disease
(CKD) are closely linked and likely promote one another. Underlying CKD now is …

Molecular nephrology: types of acute tubular injury

B Desanti De Oliveira, K Xu, TH Shen… - Nature Reviews …, 2019 - nature.com
The acute loss of kidney function has been diagnosed for many decades using the serum
concentration of creatinine—a muscle metabolite that is an insensitive and non-specific …

The association of COVID-19 with acute kidney injury independent of severity of illness: a multicenter cohort study

DG Moledina, M Simonov, Y Yamamoto… - American Journal of …, 2021 - Elsevier
Rationale & Objective Although coronavirus disease 2019 (COVID-19) has been associated
with acute kidney injury (AKI), it is unclear whether this association is independent of …

Cross-site transportability of an explainable artificial intelligence model for acute kidney injury prediction

X Song, ASL Yu, JA Kellum, LR Waitman… - Nature …, 2020 - nature.com
Artificial intelligence (AI) has demonstrated promise in predicting acute kidney injury (AKI),
however, clinical adoption of these models requires interpretability and transportability. Non …

[HTML][HTML] Epidemiology of AKI: utilizing large databases to determine the burden of AKI

S Sawhney, SD Fraser - Advances in chronic kidney disease, 2017 - Elsevier
Large observational databases linking kidney function and other routine patient health data
are increasingly being used to study acute kidney injury (AKI). Routine health care data …

Risk for chronic kidney disease progression after acute kidney injury: Findings from the chronic renal insufficiency cohort study

AN Muiru, JY Hsu, X Zhang, LJ Appel… - Annals of internal …, 2023 - acpjournals.org
Background: Prior studies associating acute kidney injury (AKI) with more rapid subsequent
loss of kidney function had methodological limitations, including inadequate control for …

Phenotyping of acute kidney injury: beyond serum creatinine

DG Moledina, CR Parikh - Seminars in nephrology, 2018 - Elsevier
Acute kidney injury (AKI) is a common complication in hospitalized patients and is
associated with adverse short-and long-term outcomes. AKI is diagnosed by serum …

[HTML][HTML] Acute kidney injury: diagnostic approaches and controversies

K Makris, L Spanou - The Clinical Biochemist Reviews, 2016 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a significant independent risk factor for morbidity and mortality. In
the last ten years a large number of publications have highlighted the limitations of …

Sex hormones in women with kidney disease

SB Ahmed, S Ramesh - Nephrology dialysis transplantation, 2016 - academic.oup.com
Menstrual disorders, infertility and premature menopause are common but often
underrecognized phenomena among women with chronic kidney disease. Hypothalamic …

Performance of serum creatinine and kidney injury biomarkers for diagnosing histologic acute tubular injury

DG Moledina, IE Hall, H Thiessen-Philbrook… - American Journal of …, 2017 - Elsevier
Background The diagnosis of acute kidney injury (AKI), which is currently defined as an
increase in serum creatinine (Scr) concentration, provides little information on the condition's …