[HTML][HTML] Isothiocyanates in medicine: A comprehensive review on phenylethyl-, allyl-, and benzyl-isothiocyanates

CC Hoch, M Shoykhet, T Weiser, L Griesbaum… - Pharmacological …, 2024 - Elsevier
In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from
Brassicaceae vegetables and herbs, have gained significant attention within the biomedical …

Anti‐Malarial Activity of Allyl Isothiocyanate and N‐acetyl‐S‐(N‐allylthiocarbamoyl)‐l‐Cysteine

T Hashimoto, S Yoshioka, S Iwanaga… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Malaria remains one of the most important infectious diseases in the world. Allyl
isothiocyanate (AITC) is a main ingredient of traditional spice Wasabia japonica, which is …

Effect of allyl isothiocyanate on oxidative stress in COPD via the AhR/CYP1A1 and Nrf2/NQO1 pathways and the underlying mechanism

WT Zhu, CH Li, TT Dai, Q Song, Y Chen, ZL Han… - Phytomedicine, 2023 - Elsevier
Background Chronic obstructive pulmonary disease (COPD) is currently the third leading
cause of death globally. Oxidative stress affects various molecular mechanisms and is the …

Effects of Allyl Isothiocyanate on Oxidative and Inflammatory Stress in Type 2 Diabetic Rats

M Okulicz, I Hertig, E Król, T Szkudelski - Molecules, 2022 - mdpi.com
Oxidative stress and inflammation play a crucial role in the pathogenesis and progression of
diabetes. Currently, there is a growing need to exploit plant-derived bioactive compounds to …

Brassica oleracea L. extract ameliorates isoproterenol-induced myocardial injury by regulating HIF-1α-mediated glycolysis

H Luan, Z Wang, Z Zhang, B Hou, Z Liu, L Yang… - Fitoterapia, 2024 - Elsevier
Brassica oleracea L.(BO) is an important vegetable with proven health benefits. This study
aimed to elucidate the constituents of BO leaf extract (BOE) and evaluate its effect on …

Therapeutic potential of epigenetic drugs

MK Gupta - Epigenetics in Human Disease, 2024 - Elsevier
Cardiovascular disease (CVD) is one of the leading causes of death, taking millions of lives
each year. Genetic mutation, lifestyle, and socioeconomic status largely contribute to the …

[HTML][HTML] Allyl isothiocyanate exacerbates acute toxoplasmosis through inhibition of inflammatory cytokines

QM Lin, HB Long, JT He, Z Zhang… - … Hosts and Diseases, 2024 - pmc.ncbi.nlm.nih.gov
Allyl isothiocyanate (AITC) is a natural product commonly used in food preservation and
pharmaceutical applications. Toxoplasmosis, caused by the protozoan pathogen …

[PDF][PDF] UNRAVELING THE MOLECULAR MECHANISM OF ALLYL ISOTHIOCYANATE (AITC) THROUGH NETWORK PHARMACOLOGICAL APPROACH; PROTEIN …

V Vijayalakshmi, H Manjunatha, PK Andrade… - 2023 - ijbbku.com
The framework of this report is based on the interpretation of the communication
path/process amid in Allyl isothiocyanate interactome to analyze the molecular …

Investigation of the effects of tadalafil on the myocardium via electrical and isometric contractions and cardiac markers in Wistar rats

DA Aykan, S Yaman, M Seyithanoğlu… - Cukurova Medical … - dergipark.org.tr
Öz Purpose: Tadalafil, a long-acting phosphodiesterase-5 (PDE-5) inhibitor, is commonly
used in the treatment of erectile dysfunction. This study investigates the contribution of …